(9CI)-1,2,3,4-四氢-3-甲基吡啶并[1,2-a]苯并咪唑合成路线 （共 7 条）
反应条件
hydrogen; dirhodium tetraacetate; triphenylphosphine T=70°C; P=20685.9 Torr;
参考文献
Anastasiou, Despina; Campi, Eva M.; Chaouk, Hassan; Jackson, W. Roy
Tetrahedron, 1992 , vol. 48, # 36 p. 7467 - 7478
反应条件
nickel in ethanol Heating;
参考文献
Panda, Kausik; Suresh; Ila; Junjappa
Journal of Organic Chemistry, 2003 , vol. 68, # 9 p. 3498 - 3506
反应条件
1: 85 percent / NaH / tetrahydrofuran 2: 78 percent / [RhCl(cis-cyclooctene)2]2; tricyclohexylphosphonium chloride / 1,2-dichloro-benzene; acetone / 0.1 h / 225 °C / microwave irradiation View Scheme
参考文献
Tan; Bergman; Ellman
Journal of the American Chemical Society, 2001 , vol. 123, # 11 p. 2685 - 2686
反应条件
1.1: NaH / tetrahydrofuran / 0.25 h / 20 °C 1.2: 85 percent / tetrahydrofuran / Heating 2.1: 71 percent / [RhCl(cis-cyclooctene)2]2; tricyclohexylphosphine / toluene / 20 h / 180 °C View Scheme
参考文献
Tan, Kian L.; Vasudevan, Anil; Bergman, Robert G.; Ellman, Jonathan A.; Souers, Andrew J.
Organic Letters, 2003 , vol. 5, # 12 p. 2131 - 2134
反应条件
1: 51 percent / Heating 2: 85 percent / iron powder, conc. hydrochloric acid / aq. ethanol 3: 78 percent / hydrogen / rhodium(II) acetate dimer, triphenylphosphine / ethyl acetate / 20 h / 70 °C / 20685.9 Torr View Scheme
参考文献
Anastasiou, Despina; Campi, Eva M.; Chaouk, Hassan; Jackson, W. Roy
Tetrahedron, 1992 , vol. 48, # 36 p. 7467 - 7478
反应条件
1: 85 percent / iron powder, conc. hydrochloric acid / aq. ethanol 2: 78 percent / hydrogen / rhodium(II) acetate dimer, triphenylphosphine / ethyl acetate / 20 h / 70 °C / 20685.9 Torr View Scheme
参考文献
Anastasiou, Despina; Campi, Eva M.; Chaouk, Hassan; Jackson, W. Roy
Tetrahedron, 1992 , vol. 48, # 36 p. 7467 - 7478
反应条件
1.1: BuLi / tetrahydrofuran / 1 h / 0 °C 1.2: 92 percent / tetrahydrofuran / 0 - 20 °C 2.1: 70 percent / H3PO4 / 5 h / 90 - 100 °C 3.1: 74 percent / Raney-Ni / ethanol / Heating View Scheme
参考文献
Panda, Kausik; Suresh; Ila; Junjappa
Journal of Organic Chemistry, 2003 , vol. 68, # 9 p. 3498 - 3506
