2-甲基-2-丙基[(1R,5S,6R)-3-氮杂双环[3.1.0]己-6-基甲基]氨基甲酸酯合成路线 （共 5 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol T=20°C; 1 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776
反应条件
1: CH3COONa; HONH2*HCl / ethanol / 16 h / 20 °C 2: LiAlH4 / tetrahydrofuran / 15 h / Heating 3: NEt3 / dioxane; H2O / 4 h / 20 °C 4: H2 / Pd/C / ethanol / 1 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776
反应条件
1: (ClCO)2; DMSO; NEt3 / CH2Cl2 / 19 h / -75 - 20 °C 2: CH3COONa; HONH2*HCl / ethanol / 16 h / 20 °C 3: LiAlH4 / tetrahydrofuran / 15 h / Heating 4: NEt3 / dioxane; H2O / 4 h / 20 °C 5: H2 / Pd/C / ethanol / 1 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776
反应条件
1: NEt3 / dioxane; H2O / 4 h / 20 °C 2: H2 / Pd/C / ethanol / 1 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776
反应条件
1: LiAlH4 / tetrahydrofuran / 48 h / Heating 2: (ClCO)2; DMSO; NEt3 / CH2Cl2 / 19 h / -75 - 20 °C 3: CH3COONa; HONH2*HCl / ethanol / 16 h / 20 °C 4: LiAlH4 / tetrahydrofuran / 15 h / Heating 5: NEt3 / dioxane; H2O / 4 h / 20 °C 6: H2 / Pd/C / ethanol / 1 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776
