四氢-2H-吡喃-4-甲烷硫酸盐合成路线

2081-44-9四氢吡喃-4-醇+124-63-0甲烷磺酰氯→134419-59-3四氢-2H-吡喃-4-甲烷硫酸盐

参考文献

Incyte Corporation; Lu, Liang; He, Chunhong; Yao, Wenqing
Patent: US2014/45814 A1, 2014 ;
Location in patent: Paragraph 0245; 0246 ;

29943-42-8四氢吡喃酮→134419-59-3四氢-2H-吡喃-4-甲烷硫酸盐

参考文献

Gruenenthal GmbH
Patent: US2012/46301 A1, 2012 ;
US 20120046301 A1

108-97-4吡喃-4-酮→134419-59-3四氢-2H-吡喃-4-甲烷硫酸盐

参考文献

Heuberger; Owen
Journal of the Chemical Society, 1952 , p. 910,913

2075-45-84-溴吡唑+134419-59-3四氢-2H-吡喃-4-甲烷硫酸盐→1040377-02-34-溴-1-(四氢-2H-吡喃-4-基)-1H-吡唑

参考文献

Zhang, Dengyou; Zhang, Xiaowei; Ai, Jing; Zhai, Yun; Liang, Zhongjie; Wang, Ying; Chen, Yi; Li, Chunpu; Zhao, Fei; Jiang, Hualiang; Geng, Meiyu; Luo, Cheng; Liu, Hong
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 21 p. 6804 - 6820

134419-59-3四氢-2H-吡喃-4-甲烷硫酸盐+10387-40-3硫代乙酸钾→203246-70-2

参考文献

Boehringer Ingelheim International GmbH
Patent: US2010/76029 A1, 2010 ;
Location in patent: Page/Page column 39 ;
US 20100076029 A1

269410-08-44-吡唑硼酸频哪醇酯+134419-59-3四氢-2H-吡喃-4-甲烷硫酸盐→1040377-03-41-(四氢吡喃-4-基)-1H-吡唑-4-硼酸频哪醇酯

参考文献

Incyte Corporation; Lu, Liang; He, Chunhong; Yao, Wenqing
Patent: US2014/45814 A1, 2014 ;
Location in patent: Paragraph 0247; 0248 ;

134419-59-3四氢-2H-吡喃-4-甲烷硫酸盐→1040377-03-41-(四氢吡喃-4-基)-1H-吡唑-4-硼酸频哪醇酯

参考文献

Zhang, Dengyou; Zhang, Xiaowei; Ai, Jing; Zhai, Yun; Liang, Zhongjie; Wang, Ying; Chen, Yi; Li, Chunpu; Zhao, Fei; Jiang, Hualiang; Geng, Meiyu; Luo, Cheng; Liu, Hong
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 21 p. 6804 - 6820

134419-59-3四氢-2H-吡喃-4-甲烷硫酸盐→116312-69-7(四氢-2H-吡喃-4-基)肼

参考文献

Ube Industries, Ltd.
Patent: EP1661894 A1, 2006 ;
Location in patent: Page/Page column 7; 12 ;

134419-59-3四氢-2H-吡喃-4-甲烷硫酸盐→3174-74-13,6-二氢-2H-吡喃

参考文献

Suto; Stier; Werbel; Arundel-Suto; Leopold; Elliott; Sebolt-Leopold
Journal of Medicinal Chemistry, 1991 , vol. 34, # 8 p. 2484 - 2488