7-甲基 lumazine合成路线 (共 9 条)
反应条件
hydrogenchloride; acetic acid; sodium nitrite
参考文献
Journal of the American Chemical Society, , vol. 74, p. 408,410
反应条件
aluminum oxide microwave irradiation;
参考文献
Singh; Geetanjali
Russian Journal of Organic Chemistry, 2006 , vol. 42, # 1 p. 136 - 138
参考文献
Chemische Berichte, , vol. 70, p. 761,765
反应条件
2: aqueous H2SO4 View Scheme
参考文献
Rimoli; Avallone; De Caprariis; Luraschi; Abignente; Filippelli; Berrino; Rossi
European Journal of Medicinal Chemistry, 1997 , vol. 32, # 3 p. 195 - 203
反应条件
sodium hydroxide T=180 - 190°C; Erhitzen des Reaktionsprodukts mit wss. H2SO4;
参考文献
Sharefkin
Journal of Organic Chemistry, 1959 , vol. 24, p. 345,348
反应条件
1: With sodium hydroxide in water 96 h; Heating / reflux; 2: With hydrogenchloride in water pH=1.5;
参考文献
ARRAY BIOPHARMA INC.
Patent: WO2005/95391 A1, 2005 ;
Location in patent: Page/Page column 39 ;
参考文献
Sharefkin
Journal of Organic Chemistry, 1959 , vol. 24, p. 345,348
参考文献
Sharefkin
Journal of Organic Chemistry, 1959 , vol. 24, p. 345,348
反应条件
2: aqueous H2SO4
4: aq.-ethanolic HCl
View Scheme
参考文献
Weijlard et al.
Journal of the American Chemical Society, 1945 , vol. 67, p. 802,804