2-甲氧基-4-硝基-5-甲基苯胺合成路线 （共 11 条）
参考文献
Queen's University at Kingston
Patent: US5989451 A1, 1999 ;
参考文献
Kolbah; Blazevic; Hannoun; et al.
Helvetica Chimica Acta, 1977 , vol. 60, # 1 p. 265 - 283
反应条件
1: glacial acetic acid; nitric acid 2: NaOH-solution View Scheme
参考文献
Kolbah; Blazevic; Hannoun; et al.
Helvetica Chimica Acta, 1977 , vol. 60, # 1 p. 265 - 283
反应条件
durch Eliminierung der Aminogruppe und darauffolgende Reduktion;
参考文献
Limpach
Chemische Berichte, 1889 , vol. 22, p. 791
Chemische Berichte, 1891 , vol. 24, p. 4140 Anm.
反应条件
(i) NaNO2, aq. HCl, (ii) H3PO2; Multistep reaction;
参考文献
Davis; Zaun; Reeves; Hance; McCord
Journal of medicinal chemistry, 1966 , vol. 9, # 6 p. 828 - 830
反应条件
sodium hydroxide; hydrogen bromide; sodium hydrogensulfite; copper(I) bromide in dichloromethane; water
参考文献
Zeneca Limited
Patent: US5444038 A1, 1995 ;
反应条件
hydrogenchloride; tin
参考文献
Limpach
Chemische Berichte, 1889 , vol. 22, p. 791
Chemische Berichte, 1891 , vol. 24, p. 4140 Anm.
反应条件
(i) NaNO2, aq. HCl, AcOH, (ii) CuCl, aq. HCl; Multistep reaction;
参考文献
Kolbah; Blazevic; Hannoun; et al.
Helvetica Chimica Acta, 1977 , vol. 60, # 1 p. 265 - 283
反应条件
1: (i) NaNO2, aq. HCl, AcOH, (ii) CuCl, aq. HCl
2: Sn, aq. HCl
View Scheme
参考文献
Kolbah; Blazevic; Hannoun; et al.
Helvetica Chimica Acta, 1977 , vol. 60, # 1 p. 265 - 283
反应条件
1: (i) NaNO2, aq. HBr, AcOH, (ii) CuBr, aq. HBr
2: KOH
View Scheme
参考文献
Kupchan; Liepa; Kameswaran; Sempuku
Journal of the American Chemical Society, 1973 , vol. 95, # 9 p. 2995 - 3000
