2,3-二甲基环己烷-1-酮合成路线 （共 23 条）
反应条件
pyridinium chlorochromate in dichloromethane
2.5 h; Ambient temperature;
参考文献
Duhamel, Pierre; Dujardin, Gilles; Hennequin, Laurent; Poirier, Jean-Marie
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 3 p. 387 - 396
反应条件
3β,17β-dihydroxy-17α-methylandrost-5-ene in diethyl ether; hexane; toluene
T=-78°C;
参考文献
Maruoka, Keiji; Nonoshita, Katsumasa; Yamamoto, Hisashi
Tetrahedron Letters, 1987 , vol. 28, # 46 p. 5723 - 5726
反应条件
MABR in dichloromethane
T=-40 - -20°C;
参考文献
Maruoka, Keiji; Sato, Junko; Yamamoto, Hisashi
Journal of the American Chemical Society, 1992 , vol. 114, # 11 p. 4422 - 4423
反应条件
[VO(OEt)Cl2] in tetrahydrofuran
T=0 - 20°C; Methylation; 20 h;
参考文献
Hirao, Toshikazu; Takada, Takashi; Sakurai, Hidehiro
Organic Letters, 2000 , vol. 2, # 23 p. 3659 - 3661
反应条件
tert.-butylhydroperoxide; anhydrous iron chloride; [(n-C4H9)4N][OsVI(N)Cl4] in dichloromethane; acetic acid
T=23°C; 0.0833333 h;
参考文献
Yiu, Shek-Man; Man, Wai-Lun; Lau, Tai-Chu
Journal of the American Chemical Society, 2008 , vol. 130, # 32 p. 10821 - 10827
反应条件
[VO(OEt)Cl2] in tetrahydrofuran
T=-78°C; Methylation; 20 h; Product distribution; Further Variations:ReagentsSolventsTemperaturesratio of reaction partners; reaction time;
参考文献
Hirao, Toshikazu; Takada, Takashi; Sakurai, Hidehiro
Organic Letters, 2000 , vol. 2, # 23 p. 3659 - 3661
反应条件
(PPh4)2[Mn(N)(CN)4]; dihydrogen peroxide; acetic acid in 2,2,2-trifluoroethanol
T=23°C; 5 h; Inert atmosphere; Reagent/catalyst;
参考文献
Ma, Li; Pan, Yi; Man, Wai-Lun; Kwong, Hoi-Ki; Lam, William W.Y.; Chen, Gui; Lau, Kai-Chung; Lau, Tai-Chu
Journal of the American Chemical Society, 2014 , vol. 136, # 21 p. 7680 - 7687
反应条件
1: 93 percent / H2 / Raney Ni / hexane / 3 h / 140 °C
2: 86 percent / CrO3, water, H2SO4 / acetone / 3 h / 20 °C
View Scheme
参考文献
Kawanobe, Tsuneo; Iwamoto, Minoru; Kogami, Kunio; Matsui, Masanao
Agricultural and Biological Chemistry, 1987 , vol. 51, # 3 p. 791 - 796
反应条件
2,6-dichloropyridine-N-oxide; tetra-n-butylammonium nitridoosmate(VIII); iron(III) chloride in dichloromethane; acetic acid
T=23°C; 16 h; Product distribution;
参考文献
Yiu, Shek-Man; Wu, Zhi-Biao; Mak, Chi-Keung; Lau, Tai-Chu
Journal of the American Chemical Society, 2004 , vol. 126, # 45 p. 14921 - 14929
反应条件
2,6-dichloropyridine-N-oxide; tetra-n-butylammonium nitridoosmate(VIII); iron(III) chloride in dichloromethane; acetic acid
T=23°C; 16 h; Product distribution;
参考文献
Yiu, Shek-Man; Wu, Zhi-Biao; Mak, Chi-Keung; Lau, Tai-Chu
Journal of the American Chemical Society, 2004 , vol. 126, # 45 p. 14921 - 14929
