(6-甲基吡啶-2-基)甲基乙酸酯合成路线 （共 13 条）
参考文献
Merck Sharp and Dohme Limited
Patent: US6255305 B1, 2001 ;
US 6255305 B1
参考文献
Weidmann, Klaus; Herling, Andreas W.; Lang, Hans-Jochen; Scheunemann, Karl-Heinz; Rippel, Robert; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 3 p. 438 - 450
反应条件
1: acetic acid; aqueous hydrogen peroxide View Scheme
参考文献
Boekelheide; Linn
Journal of the American Chemical Society, 1954 , vol. 76, p. 1286,1289
参考文献
Jones, Gurnos; Mouat, Deborah J.; Tonkinson, Daryl J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2719 - 2724
反应条件
1: diethyl ether; lithium alanate 2: sodium acetate View Scheme
参考文献
Baker et al.
Journal of the Chemical Society, 1958 , p. 3594,3601
参考文献
Baker et al.
Journal of the Chemical Society, 1958 , p. 3594,3601
参考文献
Kobayashi et al.
Yakugaku Zasshi, 1954 , vol. 74, p. 790
Chem.Abstr., 1955 , p. 11646
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Boekelheide; Linn
Journal of the American Chemical Society, 1954 , vol. 76, p. 1286,1289
反应条件
1: 2N aq. NaOH / methanol / 2 h / 25 °C 2: SOCl2 / CH2Cl2 / 2 h / 25 °C View Scheme
参考文献
Kobayashi et al.
Yakugaku Zasshi, 1954 , vol. 74, p. 790
Chem.Abstr., 1955 , p. 11646
反应条件
1: aqueous hydrochloric acid 2: manganese (IV)-oxide; diethyl ether 3: Ag2O; NH3; aqueous NaOH View Scheme
参考文献
Nakashima
Yakugaku Zasshi, 1958 , vol. 78, p. 661,665
Chem.Abstr., 1958 , p. 18399
参考文献
Weidmann, Klaus; Herling, Andreas W.; Lang, Hans-Jochen; Scheunemann, Karl-Heinz; Rippel, Robert; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 3 p. 438 - 450
