1-(2'-脱氧-beta-苏式呋喃戊糖基)腺嘌呤合成路线 （共 14 条）
反应条件
lithium triethylborohydride in tetrahydrofuran; dimethyl sulfoxide T=21°C; 14 h;
参考文献
Robins, Morris J.; Nowak, Ireneusz; Wnuk, Stanislaw F.; Hansske, Fritz; Madej, Danuta
Journal of Organic Chemistry, 2007 , vol. 72, # 22 p. 8216 - 8221
反应条件
lithium triethylborohydride in tetrahydrofuran; dimethyl sulfoxide
参考文献
Hansske, Fritz; Robins, Morris J.
Journal of the American Chemical Society, 1983 , vol. 105, # 22 p. 6736 - 6737
反应条件
silica gel; trifluoroacetic acid in methanol; chloroform
参考文献
Pathak, Ashish K.; Pathak, Vibha; Seitz, Lainne E.; Tiwari, Kamal N.; Akhtar, Mohammad S.; Reynolds, Robert C
Tetrahedron Letters, 2001 , vol. 42, # 44 p. 7755 - 7757
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 4 h;
参考文献
Robins, Morris J.; Nowak, Ireneusz; Wnuk, Stanislaw F.; Hansske, Fritz; Madej, Danuta
Journal of Organic Chemistry, 2007 , vol. 72, # 22 p. 8216 - 8221
反应条件
1: LiN3 / dimethylformamide / 4 h / 80 °C 2: H2 / 10 percent Pd/C / ethanol / 4 h 3: pyridine 4: DMAP; pyridine / 12 h 5: DCC; pyridine / dioxane View Scheme
参考文献
Reddy, Putta Mallikarjuna; Bruice, Thomas C.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 7 p. 1281 - 1285
反应条件
1: pyridine / 9 h / 0 - 20 °C 2: LiN3 / dimethylformamide / 4 h / 80 °C 3: H2 / 10 percent Pd/C / ethanol / 4 h 4: pyridine 5: DMAP; pyridine / 12 h 6: DCC; pyridine / dioxane View Scheme
参考文献
Reddy, Putta Mallikarjuna; Bruice, Thomas C.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 7 p. 1281 - 1285
反应条件
1: H2 / 10 percent Pd/C / ethanol / 4 h 2: pyridine 3: DMAP; pyridine / 12 h 4: DCC; pyridine / dioxane View Scheme
参考文献
Reddy, Putta Mallikarjuna; Bruice, Thomas C.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 7 p. 1281 - 1285
反应条件
1: 4-(dimethylamino)pyridine (DMAP) / acetonitrile / Ambient temperature 2: 1.) Bu3SnH, 2.) 5percent NaOMe / 1.) AIBN / 1.) toluene, 80 deg C, 8 h, 2.) MeOH, room temperature View Scheme
参考文献
Robins, Morris J.; Madej, Danuta; Hansske, Fritz; Wilson, John S.; Gosselin, Gilles; et al.
Canadian Journal of Chemistry, 1988 , vol. 66, p. 1258 - 1262
反应条件
1: pyridine 2: DMAP; pyridine / 12 h 3: DCC; pyridine / dioxane View Scheme
参考文献
Reddy, Putta Mallikarjuna; Bruice, Thomas C.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 7 p. 1281 - 1285
反应条件
1: DMAP; pyridine / 12 h 2: DCC; pyridine / dioxane View Scheme
参考文献
Reddy, Putta Mallikarjuna; Bruice, Thomas C.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 7 p. 1281 - 1285
