5-[2-(甲硫基)乙基]海因合成路线 （共 18 条）
反应条件
racemisation by Pseudomonas Sp.;
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 1-2 p. 91 - 95
反应条件
enzymatic hydrolysis of several hydantoines with Pseudomonas Sp.; Mechanism;
参考文献
Guivarch, Marcel; Gillonnier, Claude; Brunie, Jean-Claude
Bulletin de la Societe Chimique de France, 1980 , vol. 2, # 1-2 p. 91 - 95
反应条件
in water T=30°C; 72 h; Pseudomonas sp. strain NS671, air. pH 7.0 - 7.2; different cultivation times, other 5-substituted hydantoins; Mechanism;
参考文献
Ishikawa, Takahiro; Watabe, Ken; Mukohara, Yukuo; Kobayashi, Shinobu; Nakamura, Hiroaki
Bioscience, Biotechnology, and Biochemistry, 1993 , vol. 57, # 6 p. 982 - 986
反应条件
T=30°C; conversion by E. coli pHPB12; Product distribution;
参考文献
Guivarch, Marcel; Gillonnier, Claude; Brunie, Jean-Claude
Bulletin de la Societe Chimique de France, 1980 , vol. 2, # 1-2 p. 91 - 95
反应条件
1: With water; potassium hydroxide T=173 - 178°C; 1 h; 2: With carbon dioxide; water T=20°C; CrystallizationPresence of polyvinyl alcohol;
参考文献
Sumitomo Chemical Company, Limited
Patent: EP2133328 A2, 2009 ;
Location in patent: Page/Page column 6-7 ;
反应条件
in water T=30°C; 24 h; 0.1 M potassium phosphate buffer (pH = 8.0); bacterioal strain H-319; also H-968; Product distribution;
参考文献
Yokozeki, Kenzo; Nakamori, Shigeru; Eguchi, Chikahiko; Yamada, Kazuhiko; Mitsugi, Koji
Agricultural and Biological Chemistry, 1987 , vol. 51, # 2 p. 355 - 362
参考文献
Atkinson; Poppelsdorf
Journal of the Chemical Society, 1951 , p. 1378
反应条件
water; potassium carbonate
T=165 - 189°C; Industrial scale;
参考文献
Evonik Degussa GmbH; Steffan, Martin; Hasselbach, Hans Joachim; Koerfer, Martin; Jakob, Harald; Gangadwala, Jignesh
Patent: US2013/245318 A1, 2013 ;
Location in patent: Paragraph 0111-0119 ;
