sodium tetrahydroborate in ethanol T=20°C; 4.33333 h; Cooling with ice;

1: methanol / 20 - 22 °C 2: PbO2 / 20 - 22 °C 3: 96 percent / H2SO4 / methanol 4: 5.50 mg / NaBH4 / ethanol / 3 h / 0 °C View Scheme

1: 96 percent / H2SO4 / methanol 2: 5.50 mg / NaBH4 / ethanol / 3 h / 0 °C View Scheme

1: PbO2 / 20 - 22 °C 2: 96 percent / H2SO4 / methanol 3: 5.50 mg / NaBH4 / ethanol / 3 h / 0 °C View Scheme

1: rabbit P450 1A2 / 0.08 h 2: Na2S2O4; H2O / 0.02 h / Heating View Scheme

1: 50 percent- nitric acid / 5 °C 2: sulfurous acid View Scheme

暂无反应条件数据

sodium hydrogensulfite; sodium hydroxide in ethanol; water T=80°C; 36.5 h; Cooling with ice;

potassium hydroxide T=100°C;

1.1: 4.9 mg / NaOH; NaHSO3 / ethanol / 4 h / 70 - 80 °C 2.1: 74 percent / HBr; AcOH / 16 h / 20 °C 3.1: Li; NH3 / tetrahydrofuran; H2O / 0.75 h / -78 - -33 °C 3.2: 76 percent / tetrahydrofuran; H2O / 2 h / Heating 4.1: 98 percent / KOtBu / toluene / 4 h / Heating 5.1: 100 percent / HCl / tetrahydrofuran / 12 h / 20 °C 6.1: 89 percent / H2; Et3N / 10percent Pd/C / methanol / 12 h / 20 °C 7.1: 98 percent / KOtBu / toluene / 3 h / Heating 8.1: 4 percent / AgO; HNO3 / dioxane / 20 °C View Scheme