(S)-1-5-甲基 2-((叔丁氧基羰基)氨基)戊二酸苄酯合成路线 （共 7 条）
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane T=0 - 20°C; 0.5 h; Inert atmosphere;
参考文献
Koseki, Yohei; Yamada, Haruka; Usuki, Toyonobu
Tetrahedron Asymmetry, 2011 , vol. 22, # 5 p. 580 - 586
反应条件
potassium carbonate in acetone 4 h; Reflux;
参考文献
Stolze, Sara C.; Meltzer, Michael; Ehrmann, Michael; Kaiser, Markus
European Journal of Organic Chemistry, 2012 , # 8 p. 1616 - 1625
反应条件
in diethyl ether; ethanol T=65°C; 0.333333 h;
参考文献
Boudreault, Pierre-Luc; Voyer, Normand
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 9 p. 1459 - 1465
反应条件
in methanol; dichloromethane T=0°C;
参考文献
Jones, Kristen L.G.; Holloway, M. Katharine; Su, Hua-Poo; Carroll, Steven S.; Burlein, Christine; Touch, Sinoeun; DiStefano, Daniel J.; Sanchez, Rosa I.; Williams, Theresa M.; Vacca, Joseph P.; Coburn, Craig A.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 14 p. 4065 - 4068
反应条件
hydrogen; palladium on activated charcoal in ethanol T=20°C; P=2068.65 Torr; 2 h;
参考文献
Boudreault, Pierre-Luc; Voyer, Normand
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 9 p. 1459 - 1465
反应条件
4-(N,N-dimethlyamino)pyridine in acetonitrile T=20°C; 20 h; Inert atmosphere;
参考文献
Koseki, Yohei; Yamada, Haruka; Usuki, Toyonobu
Tetrahedron Asymmetry, 2011 , vol. 22, # 5 p. 580 - 586
反应条件
1: 4-(N,N-dimethlyamino)pyridine / acetonitrile / 20 h / 20 °C / Inert atmosphere 2: diisobutylaluminium hydride / diethyl ether; hexane / 0.13 h / -78 °C / Inert atmosphere View Scheme
参考文献
Stolze, Sara C.; Meltzer, Michael; Ehrmann, Michael; Kaiser, Markus
European Journal of Organic Chemistry, 2012 , # 8 p. 1616 - 1625
