5-(三甲基硅烷基)-4-戊炔-1-醇合成路线 （共 21 条）
反应条件
1.1: DIBAL-H / diethyl ether; hexane / 24 h / Heating
1.2: 91 percent / I2 / diethyl ether; hexane / 2 h / -78 °C
2.1: n-BuLi; TMEDA / tetrahydrofuran / 0.75 h / 0 °C
2.2: CuI / tetrahydrofuran / 0.5 h / -78 °C
2.3: 83 percent / 4-dimethylaminopyridine / tetrahydrofuran / -20 - 20 °C
View Scheme
参考文献
Heffron, Timothy P.; Jamison, Timothy F.
Organic Letters, 2003 , vol. 5, # 13 p. 2339 - 2342
