N-苯甲酰基-(2R,3S)-3-苯基异丝氨酸合成路线 （共 50 条）
反应条件
sodium hydrogencarbonate T=4°C; 6 h;
参考文献
Deng, Li; Jacobsen, Eric N.
Journal of Organic Chemistry, 1992 , vol. 57, # 15 p. 4320 - 4323
反应条件
lithium hydroxide in tetrahydrofuran; methanol; water T=20°C; 1 h;
参考文献
Torssell, Staffan; Kienle, Marcel; Somfai, Peter
Angewandte Chemie - International Edition, 2005 , vol. 44, # 20 p. 3096 - 3099
Title/Abstract Full Text View citing articles Show Details
Torssell, Staffan; Somfai, Peter
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 16-17 p. 2421 - 2430
反应条件
potassium carbonate in methanol T=23°C; 12 h;
参考文献
Gou, Da-Ming; Liu, Yeuk-Chuen; Chen, Ching-Shih
Journal of Organic Chemistry, 1993 , vol. 58, # 5 p. 1287 - 1289
反应条件
1.1: HCl; H2 / Pd(OH)2/C / ethanol / 15 h / 20 °C / 760 Torr 1.2: 77 percent / NaHCO3 / ethyl acetate / 0.25 h / 0 °C 2.1: 89 percent / LiOH*H2O / tetrahydrofuran; methanol; H2O / 1 h / 20 °C View Scheme
参考文献
Advanced Synthesis and Catalysis, , vol. 348, # 16-17 p. 2421 - 2430
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 6 h; Inert atmosphere;
参考文献
Qian, Yu; Xu, Xinfang; Jiang, Liqin; Prajapati, Dipak; Hu, Wenhao
Journal of Organic Chemistry, 2010 , vol. 75, # 21 p. 7483 - 7486
反应条件
toluene-4-sulfonic acid in methanol T=20°C; 8 h;
参考文献
Oshitari, Tetsuta; Mandai, Tadakatsu
Synlett, 2003 , # 15 p. 2374 - 2376
反应条件
sodium hydrogencarbonate in dichloromethane; water 16 h; Ambient temperature;
参考文献
Ojima, Iwao; Habus, Ivan; Zhao, Mangzhu; Zucco, Martine; Park, Young Hoon; Sun, Chung Ming; Brigaud, Thierry
Tetrahedron, 1992 , vol. 48, # 34 p. 6985 - 7012
反应条件
1: molecular sieves 4 Angstroem / Rh2(OAc)4 / CH2Cl2 / 10 h / 0 °C 2: 49.0 mg / para-toluenesulfonic acid / methanol; H2O / 1 h / 20 °C 3: HCl; H2 / Pd(OH)2 on C / ethanol / 15 h / 20 °C / 760 Torr 4: 10.5 mg / NaHCO3 / ethyl acetate / 0.25 h / 0 °C 5: 89 percent / LiOH*H2O / tetrahydrofuran; methanol; H2O / 1 h / 20 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 44, # 20 p. 3096 - 3099
反应条件
1: With water; potassium carbonate in acetone T=20°C; 0.5 h; 2: With potassium permanganate; sodium periodate in acetone T=32°C; 3 h;
参考文献
Bhatia, Sumati; Singh, Sukhdev; Kumar, Rajesh; Kumar, Amit; Olsen, Carl E.; Prasad, Ashok K.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 3 p. 379 - 386
反应条件
1.1: benzaldehyde / Rh2(OAc)4 / CH2Cl2 / 11 h / 0 °C 1.2: 61 percent / p-TsOH / methanol / 2 h / 20 °C 2.1: HCl; H2 / Pd(OH)2/C / ethanol / 15 h / 20 °C / 760 Torr 2.2: 77 percent / NaHCO3 / ethyl acetate / 0.25 h / 0 °C 3.1: 89 percent / LiOH*H2O / tetrahydrofuran; methanol; H2O / 1 h / 20 °C View Scheme
参考文献
Advanced Synthesis and Catalysis, , vol. 348, # 16-17 p. 2421 - 2430
