1: 68 percent / Bu4NF / tetrahydrofuran / 4 h / 70 °C 2: 65 percent / H2 / 10percent Pd/C / methanol / 2 h / 760 Torr / Ambient temperature 3: 1) POCl3; 2) (Bu3NH)4P2O7, Bu3N / 1) PO(OMe)3, 4 deg C, 3 h; 2) DMF, 0 deg C, 1 min View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 81 percent / pyridine / 8 h / Ambient temperature<br />2: 90 percent / pyridine / CH₂Cl₂ / 12 h / Ambient temperature<br /> <br /> &nbsp;