1,2,3,4-四氢-9-吖啶酮合成路线 （共 21 条）
反应条件
1: anthranilic acid With thionyl chloride in benzene modified Niementowski reaction; 2 h; Heating; 2: cyclohexanone in benzene T=20°C;
参考文献
Son, Jae Keun; Kim III, Seung; Jahng, Yurndong
Heterocycles, 2001 , vol. 55, # 10 p. 1981 - 1986
反应条件
lithium diisopropyl amide in tetrahydrofuran 0 deg C, then at reflux for 8-12 h;
参考文献
Chong, R.J.; Siddiqui, M.A.; Snieckus, V.
Tetrahedron Letters, 1986 , vol. 27, # 44 p. 5323 - 5326
参考文献
Cheng; Lee; Klutchko; Winters; Reynolds; Welch; Flynn; Doherty
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 24 p. 2999 - 3002
反应条件
toluene-4-sulfonic acid in butan-1-ol 24 h; Heating;
参考文献
Luo, Fen-Tair; Ravi, Vija K.; Xue, Cuihua
Tetrahedron, 2006 , vol. 62, # 40 p. 9365 - 9372
反应条件
hydrogenchloride 1 h; Heating;
参考文献
Yamato, Masatoshi; Takeuchi, Yasuo; Ikeda, Yuji
Heterocycles, 1987 , vol. 26, # 1 p. 191 - 197
反应条件
1: 73 percent / zinc chloride / chlorobenzene / 24 h / Heating 2: 80 percent / p-toluenesulfonic acid / butan-1-ol / 24 h / Heating View Scheme
参考文献
Luo, Fen-Tair; Ravi, Vija K.; Xue, Cuihua
Tetrahedron, 2006 , vol. 62, # 40 p. 9365 - 9372
反应条件
1: 95 percent / benzene / 48 h / Heating 2: 70 percent / LDA / tetrahydrofuran / 0 deg C, then at reflux for 8-12 h View Scheme
参考文献
Chong, R.J.; Siddiqui, M.A.; Snieckus, V.
Tetrahedron Letters, 1986 , vol. 27, # 44 p. 5323 - 5326
反应条件
1: 95 percent / benzene / 48 h / Heating 2: 70 percent / LDA / tetrahydrofuran / 0 deg C, then at reflux for 8-12 h View Scheme
参考文献
Yamato, Masatoshi; Takeuchi, Yasuo; Ikeda, Yuji
Heterocycles, 1987 , vol. 26, # 1 p. 191 - 197
反应条件
1: 92 percent / K2CO3, KI / dimethylformamide / 24 h / Ambient temperature 2: 90 percent / 58 h / Heating 3: 76 percent / Ac2O, pyridine / 2 h / 140 °C 4: 90 percent / 10percent HCl / 1 h / Heating View Scheme
参考文献
Yamato, Masatoshi; Takeuchi, Yasuo; Ikeda, Yuji
Heterocycles, 1987 , vol. 26, # 1 p. 191 - 197
参考文献
Reddy, P. S. N.; Bhavani, A. K. D.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1994 , vol. 33, # 7 p. 683 - 685
