5-苯基戊-4-烯基-1-醇合成路线 （共 13 条）
反应条件
1: Raney-Ni 3: H2 / Raney-Ni View Scheme
参考文献
Collins,R.F.; Davis,M.
Journal of the Chemical Society, 1961 , p. 1863 - 1879
反应条件
1: H2 / Raney-Ni / ethanol 2: aq. HBr, H2SO4 4: H2 / Raney-Ni View Scheme
参考文献
Collins,R.F.; Davis,M.
Journal of the Chemical Society, 1961 , p. 1863 - 1879
反应条件
hydrogen; platinum(IV) oxide in methanol P=2585.7 Torr;
参考文献
Collins,R.F.; Davis,M.
Journal of the Chemical Society, 1961 , p. 1863 - 1879
反应条件
1: PBr3, pyridine / diethyl ether / 12 h / Ambient temperature
3: 10 percent Turnov. / 9,10-dicyanoanthracene (DCA) / benzene / Irradiation
View Scheme
参考文献
Woelfle, Ingrid; Chan, Samantha; Schuster, Gary B.
Journal of Organic Chemistry, 1991 , vol. 56, # 26 p. 7313 - 7319
反应条件
1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 18 h / 20 °C / Inert atmosphere
2: tri-n-butyl-tin hydride / α,α,α-trifluorotoluene / 3 h / Inert atmosphere; Irradiation
View Scheme
参考文献
Chowdhury, Nilanjana; Anoop, Anakuthil; Singh, N.D. Pradeep
Synthesis (Germany), 2012 , vol. 44, # 11 art. no. SS-2012-N1173-OP, p. 1745 - 1754
反应条件
1: 89 percent / I2; PPh3; imidazole / CH2Cl2 / 0 - 20 °C
2: 47 percent / cesium carbonate / acetonitrile / 72 h / 20 °C
View Scheme
参考文献
Belanger, Guillaume; Levesque, Francois; Paquet, Julie; Barbe, Guillaume
Journal of Organic Chemistry, 2005 , vol. 70, # 1 p. 291 - 296
反应条件
1: 89 percent / I2; PPh3; imidazole / CH2Cl2 / 0 - 20 °C
2: 47 percent / cesium carbonate / acetonitrile / 72 h / 20 °C
3: 74 percent / H2O / tetrahydrofuran / 4 h / 165 °C / microwave irradiation
View Scheme
参考文献
Belanger, Guillaume; Levesque, Francois; Paquet, Julie; Barbe, Guillaume
Journal of Organic Chemistry, 2005 , vol. 70, # 1 p. 291 - 296
反应条件
1: 87 percent / DMSO; oxalyl chloride; triethylamine / CH2Cl2 / 5.25 h / -78 - 20 °C
2: 49 percent / BH3*HNMe2 / methanol / 3 h / 20 °C
View Scheme
参考文献
Belanger, Guillaume; Levesque, Francois; Paquet, Julie; Barbe, Guillaume
Journal of Organic Chemistry, 2005 , vol. 70, # 1 p. 291 - 296
反应条件
1: 87 percent / DMSO; oxalyl chloride; triethylamine / CH2Cl2 / 5.25 h / -78 - 20 °C
2: 49 percent / BH3*HNMe2 / methanol / 3 h / 20 °C
3: 77 percent / cesium carbonate / acetonitrile / 72 h / 20 °C
4: 61 percent / H2O / tetrahydrofuran / 4 h / 165 °C / microwave irradiation
View Scheme
参考文献
Belanger, Guillaume; Levesque, Francois; Paquet, Julie; Barbe, Guillaume
Journal of Organic Chemistry, 2005 , vol. 70, # 1 p. 291 - 296
反应条件
1: 95 percent / imidazole / dimethylformamide / 0 - 20 °C
2: 72 percent / m-CPBA; NaOAc / CH2Cl2 / 6 h / 20 °C
View Scheme
参考文献
Seiders II, John R.; Wang, Lijun; Floreancig, Paul E.
Journal of the American Chemical Society, 2003 , vol. 125, # 9 p. 2406 - 2407
