N-(N-((苯甲酰氧基)羰基)-L-苯丙氨酰)-L-缬氨酸合成路线 （共 8 条）
反应条件
triethylamine in water; acetonitrile T=20°C;
参考文献
Katritzky, Alan R.; Suzuki, Kazuyuki; Singh, Sandeep K.
Synthesis, 2004 , # 16 p. 2645 - 2652
反应条件
triethylamine in tetrahydrofuran; water T=24°C; 0.5 h;
参考文献
Sosnovsky; Prakash; Rao
Journal of Pharmaceutical Sciences, 1993 , vol. 82, # 1 p. 1 - 10
反应条件
1: 78 percent / dicyclohexylcarbodiimide (DCC) / tetrahydrofuran / 6 h / 24 °C 2: 48 percent / triethylamine / tetrahydrofuran; H2O / 0.5 h / 24 °C View Scheme
参考文献
Katritzky, Alan R.; Suzuki, Kazuyuki; Singh, Sandeep K.
Synthesis, 2004 , # 16 p. 2645 - 2652
反应条件
in trifluoroacetic acid 2 h; Ambient temperature;
参考文献
Takuma; Hamada; Shioiri
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 9 p. 3147 - 3153
反应条件
1: 94 percent / DPPA, TEA / 0 deg C, 4h, room temp. overnight 2: 79 percent / trifluoroacetic acid / 2 h / Ambient temperature View Scheme
参考文献
Takuma; Hamada; Shioiri
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 9 p. 3147 - 3153
反应条件
triethylamine in 1,4-dioxane
参考文献
Losse,G. et al.
Justus Liebigs Annalen der Chemie, 1965 , vol. 684, p. 236 - 242
反应条件
in water T=0°C; 0.5 h;
参考文献
Noguchi, Takuya; Tehara, Naoka; Uesugi, Yuki; Jung, Seunghee; Imai, Nobuyuki
Chemistry Letters, 2012 , vol. 41, # 1 p. 42 - 43
参考文献
Schnabel,E. et al.
Justus Liebigs Annalen der Chemie, 1967 , vol. 707, p. 227 - 241
