ammonia in methanol T=20°C;

tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C;

1: 81 percent / silver oxide / acetone / 72 h / 20 °C 2: 80 percent / triethylamine / ethanol / 72 h / 20 °C 3: 95 percent / tetrabutylammonium fluoride / tetrahydrofuran / 20 °C View Scheme

1: 80 percent / triethylamine / ethanol / 72 h / 20 °C 2: 95 percent / tetrabutylammonium fluoride / tetrahydrofuran / 20 °C View Scheme

1: 1.) triethylamine, 2-mesitylenesulfonyl chloride, N,N-dimethylaminopyridine, 2.) 1,4-diazabicyclo<2.2.2>octane / 1.) dichloromethane, 30 min, 2.) dichloromethane, 60 min 2: 1.12 g / p-toluenesulfonic acid / CH2Cl2 / 0.03 h / 20 °C 3: 81 percent / silver oxide / acetone / 72 h / 20 °C 4: 80 percent / triethylamine / ethanol / 72 h / 20 °C 5: 95 percent / tetrabutylammonium fluoride / tetrahydrofuran / 20 °C View Scheme

1: pyridine / 20 °C 2: triethylamine / CH2Cl2 / 0.25 h / 20 °C 3: 1.) triethylamine, 2-mesitylenesulfonyl chloride, N,N-dimethylaminopyridine, 2.) 1,4-diazabicyclo<2.2.2>octane / 1.) dichloromethane, 30 min, 2.) dichloromethane, 60 min 4: 1.12 g / p-toluenesulfonic acid / CH2Cl2 / 0.03 h / 20 °C 5: 81 percent / silver oxide / acetone / 72 h / 20 °C 6: 80 percent / triethylamine / ethanol / 72 h / 20 °C 7: 95 percent / tetrabutylammonium fluoride / tetrahydrofuran / 20 °C View Scheme

1: triethylamine / CH2Cl2 / 0.25 h / 20 °C 2: 1.) triethylamine, 2-mesitylenesulfonyl chloride, N,N-dimethylaminopyridine, 2.) 1,4-diazabicyclo<2.2.2>octane / 1.) dichloromethane, 30 min, 2.) dichloromethane, 60 min 3: 1.12 g / p-toluenesulfonic acid / CH2Cl2 / 0.03 h / 20 °C 4: 81 percent / silver oxide / acetone / 72 h / 20 °C 5: 80 percent / triethylamine / ethanol / 72 h / 20 °C 6: 95 percent / tetrabutylammonium fluoride / tetrahydrofuran / 20 °C View Scheme

in methanol; N,N-dimethyl-formamide T=70°C; 1 h; Title compound not separated from byproducts;