1,1-二氧代-3-羟基-四氢噻吩合成路线 （共 8 条）
反应条件
dihydrogen peroxide; acetic acid in water
参考文献
US6191140 B1, ;
US 6191140 B1
US6642222 B2, ;
US 6642222 B2
反应条件
potassium hydroxide in 1,4-dioxane; water 5 h; Heating;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 16, # 11 p. 1122 - 1124
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 16, # 11 p. 1482 - 1484
反应条件
3-chloro-benzenecarboperoxoic acid in chloroform 1) 0 deg C, 1 h, 2) room temp., 30 min;
参考文献
Journal of Heterocyclic Chemistry, , vol. 27, # 5 p. 1453 - 1456
反应条件
triethylamine in 1,4-dioxane; water 5 h; Heating;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 16, # 11 p. 1122 - 1124
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 16, # 11 p. 1482 - 1484
反应条件
sodium carbonate in water 5 h; Heating;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 16, # 11 p. 1122 - 1124
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 16, # 11 p. 1482 - 1484
反应条件
water 10 h; Heating; Product distribution;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 16, # 11 p. 1122 - 1124
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 16, # 11 p. 1482 - 1484
反应条件
jones reagent in acetone
参考文献
GALAPAGOS NV; MENET, Christel Jeanne Marie; SCHMITT, Benoît Antoine; GENEY, Raphaël Jean Joël; DOYLE, Kevin James; PEACH, Joanne; PALMER, Nicholas John; JONES, Graham Peter; HARDY, David; DUFFY, James Edward Stewart
Patent: WO2013/117645 A1, 2013 ;
Location in patent: Paragraph 00570 ;
参考文献
Abbott Laboratories
Patent: US6191140 B1, 2001 ;
US 6191140 B1
Title/Abstract Full Text Show Details
Abbott Laboratories
Patent: US6642222 B2, 2003 ;
US 6642222 B2
