4-(2-苯基乙基)苯胺合成路线 （共 21 条）
反应条件
1: phosphorus pentoxide on alumina / 6 h / |Reflux 2: palladium 10 on activated carbon; hydrogenchloride; hydrogen / water; methanol / 24 h / 2585.81 Torr View Scheme
参考文献
Mosberg, Henry I.; Yeomans, Larisa; Harland, Aubrie A.; Bender, Aaron M.; Sobczyk-Kojiro, Katarzyna; Anand, Jessica P.; Clark, Mary J.; Jutkiewicz, Emily M.; Traynor, John R.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 5 p. 2139 - 2149
反应条件
1: palladium dichloride; potassium carbonate / acetone; water / 0.17 h / 110 °C / |Microwave irradiation 2: palladium 10 on activated carbon; hydrogenchloride; hydrogen / water; methanol / 24 h / 2585.81 Torr View Scheme
参考文献
Mosberg, Henry I.; Yeomans, Larisa; Harland, Aubrie A.; Bender, Aaron M.; Sobczyk-Kojiro, Katarzyna; Anand, Jessica P.; Clark, Mary J.; Jutkiewicz, Emily M.; Traynor, John R.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 5 p. 2139 - 2149
反应条件
1: palladium dichloride; potassium carbonate / acetone; water / 0.17 h / 110 °C / |Microwave irradiation 2: palladium 10 on activated carbon; hydrogenchloride; hydrogen / water; methanol / 24 h / 2585.81 Torr View Scheme
参考文献
Mosberg, Henry I.; Yeomans, Larisa; Harland, Aubrie A.; Bender, Aaron M.; Sobczyk-Kojiro, Katarzyna; Anand, Jessica P.; Clark, Mary J.; Jutkiewicz, Emily M.; Traynor, John R.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 5 p. 2139 - 2149
反应条件
methanol; nickel; hydrazine hydrate
参考文献
Kurssanow; Kitschkina
Zhurnal Obshchei Khimii, 1935 , vol. 5, p. 1342,1344
Chem. Zentralbl., 1936 , vol. 107, # II p. 1534
反应条件
1: benzene; AlCl3; carbon disulfide 2: tin (II)-chloride; aq.-ethanolic hydrochloric acid View Scheme
参考文献
Kurssanow; Kitschkina
Zhurnal Obshchei Khimii, 1935 , vol. 5, p. 1342,1344
Chem. Zentralbl., 1936 , vol. 107, # II p. 1534
反应条件
1: concentrated H2SO4; HNO3 2: benzene; AlCl3; carbon disulfide 3: tin (II)-chloride; aq.-ethanolic hydrochloric acid View Scheme
参考文献
Kurssanow; Kitschkina
Zhurnal Obshchei Khimii, 1935 , vol. 5, p. 1342,1344
Chem. Zentralbl., 1936 , vol. 107, # II p. 1534
反应条件
1: Aliumynium chloride 2: concentrated hydrochloric acid / 140 - 150 °C View Scheme
参考文献
v. Braun; Deutsch; Koscielski
Chemische Berichte, 1913 , vol. 46, p. 1516
参考文献
Buu-Hoi; Royer
Bulletin de la Societe Chimique de France, 1947 , p. 820
反应条件
man stellt das Nitril dar und erhitzt dieses mit Salzsaeure auf 120grad;
参考文献
v. Braun; Deutsch; Koscielski
Chemische Berichte, 1913 , vol. 46, p. 1516
参考文献
Hong, Seoung-Soo; Dukat, Malgorzata; Teitler, Milt; Herrick-Davis, Kathy; McCallum, Kirk; et al.
Medicinal Chemistry Research, 1995 , vol. 5, # 9 p. 690 - 699
