4-(2-苯基乙基)苯胺合成路线 （共 21 条）
反应条件
hydrogen; 10percent Pd/C in methanol
参考文献
Carrigan, Christina N.; Bartlett, Richard D.; Esslinger, C. Sean; Cybulski, Kimberly A.; Tongcharoensirikul, Pakamas; Bridges, Richard J.; Thompson, Charles M.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 11 p. 2260 - 2276
反应条件
1: With sodium acetate in N,N-dimethyl acetamide T=100°C; Heck reaction; Inert atmosphere; 2: With hydrogen in N,N-dimethyl acetamide T=20°C; P=760.051 Torr;
参考文献
Kantam, M. Lakshmi; Chakravarti, Rajashree; Chintareddy, Venkat Reddy; Sreedhar; Bhargava, Suresh
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 16 p. 2544 - 2550
反应条件
1: With sodium acetate in N,N-dimethyl acetamide T=100°C; Heck reaction; Inert atmosphere; 2: With hydrogen in N,N-dimethyl acetamide T=20°C; P=760.051 Torr;
参考文献
Kantam, M. Lakshmi; Chakravarti, Rajashree; Chintareddy, Venkat Reddy; Sreedhar; Bhargava, Suresh
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 16 p. 2544 - 2550
反应条件
1: With tetrabutylammomium bromide; sodium acetate in N,N-dimethyl acetamide T=100°C; Heck reaction; Inert atmosphere; 2: With hydrogen in N,N-dimethyl acetamide T=20°C; P=760.051 Torr;
参考文献
Kantam, M. Lakshmi; Chakravarti, Rajashree; Chintareddy, Venkat Reddy; Sreedhar; Bhargava, Suresh
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 16 p. 2544 - 2550
反应条件
hydrazine hydrate in ethanol T=70°C; 14 h; chemoselective reaction;
参考文献
Wang, Liuchang; Zheng, Yanjun; Zhang, Xiquan; Gu, Hongmei; Li, Jiang; Wang, Wei; Li, Baolin
Applied Catalysis A: General, 2013 , vol. 456, p. 23 - 29
反应条件
hydrogenchloride; palladium 10 on activated carbon; hydrogen in methanol; water P=2585.81 Torr; 24 h;
参考文献
Mosberg, Henry I.; Yeomans, Larisa; Harland, Aubrie A.; Bender, Aaron M.; Sobczyk-Kojiro, Katarzyna; Anand, Jessica P.; Clark, Mary J.; Jutkiewicz, Emily M.; Traynor, John R.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 5 p. 2139 - 2149
反应条件
formic acid; triethylamine; palladium on activated charcoal 18 h; Heating;
参考文献
Weir, John R.; Patel, Babu A.; Heck, Richard F.
Journal of Organic Chemistry, 1980 , vol. 45, # 24 p. 4926 - 4931
反应条件
1: 86 percent / triphenylposphine / palladium acetate / triethylamine / 1.25 h / 100 °C 2: 71 percent / HCO2H (97percent), Et3N / 10percent Pd/C / 18 h / Heating View Scheme
参考文献
Weir, John R.; Patel, Babu A.; Heck, Richard F.
Journal of Organic Chemistry, 1980 , vol. 45, # 24 p. 4926 - 4931
反应条件
1: Aliumynium chloride 2: concentrated hydrochloric acid / 140 - 150 °C View Scheme
参考文献
Mosberg, Henry I.; Yeomans, Larisa; Harland, Aubrie A.; Bender, Aaron M.; Sobczyk-Kojiro, Katarzyna; Anand, Jessica P.; Clark, Mary J.; Jutkiewicz, Emily M.; Traynor, John R.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 5 p. 2139 - 2149
反应条件
hydrogenchloride T=140 - 150°C;
参考文献
v. Braun; Deutsch; Koscielski
Chemische Berichte, 1913 , vol. 46, p. 1516
