(4-氯苯基)-氧代乙腈合成路线 (共 33 条)
反应条件
beim Erwaermen; unter Entwicklung von Stickoxyden;
参考文献
Zimmermann
Journal fuer Praktische Chemie (Leipzig), 1902 , vol. <2> 66, p. 374
反应条件
sodium bromide; sulfuric acid in ethanol
参考文献
American Cyanamid Company
Patent: US5508251 A1, 1996 ;
反应条件
hydrazine hydrate; acetic acid in ethanol T=50°C; 7 h; Overall yield = 80 percent;
参考文献
Russian Journal of Organic Chemistry, , vol. 48, # 8 p. 1111 - 1120
Zh. Org. Khim., , vol. 48, # 8 p. 1113 - 1121,9
反应条件
lithium aluminium tetrahydride in diethyl ether 1.) RT, 18 h, 2.) reflux, 6 h;
参考文献
Wrigglesworth, Roger; Walpole, Christopher S. J.; Bevan, Stuart; Campbell, Elizabeth A.; Dray, Andy; Hughes, Glyn A.; James, Iain; Masdin, Kay J.; Winter, Janet
Journal of Medicinal Chemistry, 1996 , vol. 39, # 25 p. 4942 - 4951
反应条件
hydroxylamine hydrochloride; sodium acetate in ethanol 1 h; Heating;
参考文献
Lakhan, Ram; Singh, Om Prakash
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, p. 690 - 692
反应条件
tetrakis(triphenylphosphine) palladium(0) in benzene T=120°C; 12 h;
参考文献
Murahashi, Shun-Ichi; Naota, Takeshi; Nakajima, Nobuyuki
Journal of Organic Chemistry, 1986 , vol. 51, # 6 p. 898 - 901
反应条件
magnesium iodide in tetrahydrofuran T=20°C; 7 h;
参考文献
Saikia, Promod; Laskar, Dhrubojyoti D.; Prajapati, Dipak; Sandhu, Jagir S.
Tetrahedron Letters, 2002 , vol. 43, # 42 p. 7525 - 7526
反应条件
in acetonitrile T=25°C;
参考文献
Tetrahedron Letters, , vol. 24, # 43 p. 4723 - 4726
参考文献
Achmatowicz,O.; Achmatowicz,O.
Roczniki Chemii, 1961 , vol. 35, p. 813 - 820
反应条件
L-proline T=20°C; 10 h;
参考文献
Shen, Zongxuan; Li, Bin; Wang, Lu; Zhang, Yawen
Tetrahedron Letters, 2005 , vol. 46, # 50 p. 8785 - 8788