3-(三氟甲基)-1H-吡唑-5-羧酸乙酯合成路线 （共 4 条）
反应条件
triethylamine in tetrahydrofuran 120 h; Ambient temperature;
参考文献
Jin, Fuqiang; Xu, Yuanyao; Ma, Yiling
Tetrahedron Letters, 1992 , vol. 33, # 41 p. 6161 - 6164
反应条件
1: sodium acetate / N,N-dimethyl-formamide / 20 °C / |Schlenk technique 2: N,N-dimethyl-formamide; toluene; water / 5 h / 45 °C / |Schlenk technique View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 24 p. 6255 - 6258
反应条件
in water; N,N-dimethyl-formamide; toluene T=45°C; 5 h; Schlenk technique; regioselective reaction;
参考文献
Li, Feng; Nie, Jing; Sun, Long; Zheng, Yan; Ma, Jun-An
Angewandte Chemie - International Edition, 2013 , vol. 52, # 24 p. 6255 - 6258
反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C 2.1: sodium hydroxide / 24 h 2.2: 0 °C View Scheme
参考文献
Li, Feng; Nie, Jing; Sun, Long; Zheng, Yan; Ma, Jun-An
Angewandte Chemie - International Edition, 2013 , vol. 52, # 24 p. 6255 - 6258
