4-氯-2H-吡喃-2-酮合成路线 （共 4 条）
反应条件
acetic acid; zinc T=20°C; 42 h;
参考文献
Afarinkia, Kamyar; Bearpark, Michael J.; Ndibwami, Alexis
Journal of Organic Chemistry, 2003 , vol. 68, # 19 p. 7158 - 7166
反应条件
copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride in toluene T=25°C; Sonogashira cross-coupling; 21 h;
参考文献
Fairlamb, Ian J. S.; Lee, Adam F.; Loe-Mie, Faidjiba E. M.; Niemelae, Elina H.; O'Brien, Ciara T.; Whitwood, Adrian C.
Tetrahedron, 2005 , vol. 61, # 41 p. 9827 - 9838
反应条件
1: With tetrakis(triphenylphosphine) palladium(0); hexamethyl-distannane in tetrahydrofuran
44 h; Heating;
2: With iodine in chloroform
T=20°C; 144 h;
参考文献
Afarinkia, Kamyar; Bearpark, Michael J.; Ndibwami, Alexis
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1122 - 1133
反应条件
1: With tetrakis(triphenylphosphine) palladium(0); hexamethyl-distannane in tetrahydrofuran
44 h; Heating;
2: With bromine in chloroform
T=-60 - 20°C;
参考文献
Afarinkia, Kamyar; Bearpark, Michael J.; Ndibwami, Alexis
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1122 - 1133
