(9CI)-3-乙炔-2,5-二甲基噻吩合成路线 （共 4 条）
反应条件
ethyl-lithium in diethyl ether T=-55°C; 0.5 h;
参考文献
Nishida, Masakazu; Fujii, Shozo; Aoki, Toshiki; Hayakawa, Yoshio; Muramatsu, Hiroshige; Morita, Tomohiko
Journal of Fluorine Chemistry, 1990 , vol. 46, # 3 p. 445 - 459
反应条件
1: 1) n-butyllithium / 1) diethyl ether, -30 deg C, 1h, 2) <-50 deg C 2: 64 percent / ethyllithium / diethyl ether / 0.5 h / -55 °C View Scheme
参考文献
Nishida, Masakazu; Fujii, Shozo; Aoki, Toshiki; Hayakawa, Yoshio; Muramatsu, Hiroshige; Morita, Tomohiko
Journal of Fluorine Chemistry, 1990 , vol. 46, # 3 p. 445 - 459
反应条件
1: iodine; iodic acid; acetic acid / tetrachloromethane; water 2: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine; triphenylphosphine / tetrahydrofuran 3: methanol; potassium carbonate View Scheme
参考文献
Raster, Peter; Weiss, Stefan; Hilt, Gerhard; Koenig, Burkhard
Synthesis, 2011 , # 6 art. no. Z09511SS, p. 905 - 908
反应条件
1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine; triphenylphosphine / tetrahydrofuran 2: methanol; potassium carbonate View Scheme
参考文献
Raster, Peter; Weiss, Stefan; Hilt, Gerhard; Koenig, Burkhard
Synthesis, 2011 , # 6 art. no. Z09511SS, p. 905 - 908
