sodium tetrahydroborate in dichloromethane; trifluoroacetic acid B-compd. addn. to stirred Fe-complex soln., mixt. stirring at 25°C for 1 h, diln. (CH2Cl2), quenching in aq. NaOH, org. layer sepn., drying over Na2SO4, solvent removal; residue flash chromy. (SiO2, Et2O/hexanes 1:9);

ammonia; zinc(II) chloride in tetrahydrofuran; diethyl ether; water stirring (room temp., 10 h), Et2O and NH3(aq) addn.; extg. (Et2O), drying (Na2SO4), evapn., chromy. (SiO2, hexanes / Et2O = 9: 1);

samarium diiodide in tetrahydrofuran N2-atmosphere; molar ratio SmI2:ferrocene derivative:water=16:1:40, refluxing for 16 h; hexane addn., filtration over SiO2 (elution with AcOEt), chromy. (SiO2, 3percent AcOEt in hexane);

boron trifluoride diethyl etherate in tetrahydrofuran; ammonium hydroxide; dichloromethane addn. of BF3*OEt2 to a stirred soln. of the 1,1'-diacylferrocene in THF at 25°C, addn. of NaBH3CN over 10 min, stirring (1 h), diln. withCH2Cl2, addn. of aq. NH3 to pH 10; layer sepn., drying (Na2SO4), concn., flash chromy. (SiO2; hexanes/Et2O);

NaBH4/H2SO4 in 1,4-dioxane stirring (5-20 min); excess water addn., extraction (chloroform), extract washing (water), drying, evapn., rectystn. (alcohol) or chromy.;

in tetrahydrofuran 6 equiv of borane, THF, reflux, 15 min;

in tetrahydrofuran BH3*THF (1.1 equiv. of a 0.8 M solution in THF) added at room temp. to asoln. of the ferrocenyl ketone (1.0 equiv.) in THF, stirred at room tem p. overnight, water added; extracted with chloroform, dried (MgSO4), concentrated in vacuo, crude product purified by flash column chromatography on silica gel (TLC Rf 0.56 (hexane)), elem. anal.;

platinum(IV) oxide; hydrogen in ethyl acetate; benzene stirred for 2 h under 48 psi H2;

in propan-1-ol; water Kinetics; 30°C, 50percent aq. 1-propanol, 0.01 M pH 7.0 phosphate buffer, 0.1 M and 0.2 M NaClO4, 15-20-fold excess BNAH;

methyl iodide; t-BuOH; Pd/C in tetrahydrofuran under N2 atm. MeI was added to mixt. ferrocenes in THF, refluxed for 16 h, volatiles were removed in vacuo, t-BuOH and t-BuOK were added, refluxed for 15 h, cooled, CH2Cl2+H2O were added, org. phase was evapd., dissolved in EtOH, H2-Pd/C, 7 h; react. mixt. was filtered through Celite, filtrate was evapd. in vacuo, reversed-phase HPLC;