1: 91 percent / H2 / 10percent Pd/C / methanol / 2 h 2: 82 percent / N-bromosuccinimide / methanol / 5 h / Ambient temperature 3: 62 percent / 18-crown-6 / acetonitrile / 120 h / Heating View Scheme

hydrogen; palladium on activated charcoal in methanol 2 h;

<b>Multi-step reaction with 2 steps<br /> </b>1: tetrahydrofuran / 0.5 h / -25 &deg;C<br /> <br /> &nbsp;