2,2-二甲基-1,3-丙二醇合成路线 （共 467 条）
参考文献
Bulletin de la Societe Chimique de France, , p. 2755
反应条件
in chloroform-d1 T=20°C; 0.1 h; Title compound not separated from byproducts.;
参考文献
Roy, Chandra D.; Brown, Herbert C.
Monatshefte fur Chemie, 2007 , vol. 138, # 9 p. 879 - 887
反应条件
chloro-trimethyl-silane; sodium bromide in acetonitrile 4 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Canadian Journal of Chemistry, , vol. 67, # 5 p. 816 - 819
反应条件
tetrakis(dimethylamino)diboron in toluene T=20 - 105°C; 1.03333 h;
参考文献
BORON MOLECULAR PTY LTD
Patent: WO2004/76467 A1, 2004 ;
Location in patent: Page 15 ;
反应条件
potassium acetate T=80°C;
参考文献
Bello, Charles S.; Schmidt-Leithoff, Joachim
Tetrahedron Letters, 2012 , vol. 53, # 46 p. 6230 - 6235,6
反应条件
in diethyl ether N2-atmosphere; addn. of 2 equiv. diol to B-compd., stirring for at room temp. for 5 h; cooling to -78°C, addn. of excess 1 M HCl in Et2O, slow warming to room temp., solvent removal (vac.), extn. into hexane (Soxhlet), recrystn. (hexane/CH2Cl2=9:1); elem. anal.;
参考文献
Lawlor, Fiona J.; Norman, Nicholas C.; Pickett, Nigel L.; Robins, Edward G.; Nguyen, Paul; Lesley, Gerry; Marder, Todd B.; Ashmore, Jennifer A.; Green, Jennifer C.
Inorganic Chemistry, 1998 , vol. 37, # 20 p. 5282 - 5288
反应条件
ammonia; hydrogen; Co-Fe catalyst T=210°C; P=37503 - 112509 Torr; Product distribution;
参考文献
Fischer, Achim; Mallat, Tamas; Baiker, Alfons
Angewandte Chemie - International Edition, 1999 , vol. 38, # 3 p. 351 - 354
反应条件
1: para-chloro-benzonitrile; tri-isopropoxy-borane; lithium diisopropyl amide 2: 3-hydroxy-2,2-dimethylpropanol Title compound not separated from byproducts;
参考文献
Lysen, Morten; Hansen, Henriette M.; Begtrup, Mikael; Kristensen, Jesper L.
Journal of Organic Chemistry, 2006 , vol. 71, # 6 p. 2518 - 2520
反应条件
1: 4-pyridinecarbonitrile With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; tri-isopropoxy-borane in tetrahydrofuran T=-78 - 20°C; 2: 3-hydroxy-2,2-dimethylpropanol With acetic acid in tetrahydrofuran T=20°C; 1 h;
参考文献
Hansen, Henriette M.; Lysen, Morten; Begtrup, Mikael; Kristensen, Jesper L.
Tetrahedron, 2005 , vol. 61, # 42 p. 9955 - 9960
反应条件
in tetrahydrofuran Esterification; 24 h; Heating;
参考文献
Chaumeil; Signorella; Le Drian
Tetrahedron, 2000 , vol. 56, # 49 p. 9655 - 9662
