125971-86-0合成路线

参考文献

Chen, Bang-Chi; Sundeen, Joseph E.; Guo, Peng; Bednarz, Mark S.; Hangeland, Jon J.; Ahmed, Syed Z.; Jemal, Mohammed
Journal of Labelled Compounds and Radiopharmaceuticals, 2000 , vol. 43, # 3 p. 261 - 270

444577-70-2N,3-二苯基-2-(2-甲基-1-氧代丙基)4-氧代-N-苯丁酰胺+

125971-86-0

1105067-91-1脱氟阿托伐他汀缩丙酮叔丁酯

参考文献

Stach, Jan; Havlicek, Jaroslav; Placek, Lukas; Radl, Stanislav
Collection of Czechoslovak Chemical Communications, 2008 , vol. 73, # 2 p. 229 - 246

125971-86-0+

125971-96-2阿托伐他汀中间体M4

125995-03-1阿托伐他汀内酯

参考文献

Warner-Lambert Company
Patent: US5103024 A1, 1992 ;

125971-86-0

134523-00-5阿托伐他汀

参考文献

Kawato, Yuji; Iwata, Mitsutaka; Yazaki, Ryo; Kumagai, Naoya; Shibasaki, Masakatsu
Tetrahedron, 2011 , vol. 67, # 35 p. 6539 - 6546

125971-86-0

134523-01-6阿伐他汀钠

参考文献

Tetrahedron Letters, , vol. 33, # 17 p. 2283 - 2284

125971-86-0+

125971-96-2阿托伐他汀中间体M4

125971-95-1(4R-cis)-6-[2-[2-(4-氟苯基)-5-(1-异丙基)-3-苯基-4-[(苯胺)羰基]-1H-吡咯-1-基]乙基]-2,2-二甲基-1,3-二氧己环-4-乙酸叔丁酯

参考文献

Baumann; Butler; Deering; Mennen; Millar; Nanninga; Palmer; Roth
Tetrahedron Letters, 1992 , vol. 33, # 17 p. 2283 - 2284

1331869-19-2+

125971-86-0

125971-95-1(4R-cis)-6-[2-[2-(4-氟苯基)-5-(1-异丙基)-3-苯基-4-[(苯胺)羰基]-1H-吡咯-1-基]乙基]-2,2-二甲基-1,3-二氧己环-4-乙酸叔丁酯

参考文献

Kawato, Yuji; Iwata, Mitsutaka; Yazaki, Ryo; Kumagai, Naoya; Shibasaki, Masakatsu
Tetrahedron, 2011 , vol. 67, # 35 p. 6539 - 6546

125971-86-0+

125971-96-2阿托伐他汀中间体M4

1116118-82-1+

125971-95-1(4R-cis)-6-[2-[2-(4-氟苯基)-5-(1-异丙基)-3-苯基-4-[(苯胺)羰基]-1H-吡咯-1-基]乙基]-2,2-二甲基-1,3-二氧己环-4-乙酸叔丁酯

参考文献

TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC.
Patent: WO2009/23260 A2, 2009 ;
Location in patent: Page/Page column 23 ;

125971-95-1(4R-cis)-6-[2-[2-(4-氟苯基)-5-(1-异丙基)-3-苯基-4-[(苯胺)羰基]-1H-吡咯-1-基]乙基]-2,2-二甲基-1,3-二氧己环-4-乙酸叔丁酯

参考文献

M. J. Institute of Research
Patent: EP2075246 A1, 2009 ;
Location in patent: Page/Page column 19; 20 ;

125971-86-0+

125971-96-2阿托伐他汀中间体M4+

67-63-0异丙醇

125971-95-1(4R-cis)-6-[2-[2-(4-氟苯基)-5-(1-异丙基)-3-苯基-4-[(苯胺)羰基]-1H-吡咯-1-基]乙基]-2,2-二甲基-1,3-二氧己环-4-乙酸叔丁酯

参考文献

Warner-Lambert Company
Patent: US5103024 A1, 1992 ;