2-(噻吩-2-基)嘧啶-4-醇合成路线 （共 3 条）
反应条件
potassium carbonate in ethanol T=80°C;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED; WANG, Tiansheng; HANZELKA, Brian; MUH, Ute; BEMIS, Guy; ZUCCOLA, Harmon, J.
Patent: WO2011/19405 A1, 2011 ;
Location in patent: Page/Page column 199 ;
WO 2011/019405 A1
反应条件
T=180°C; 0.0833333 h;
参考文献
ARGENTA DISCOVERY LIMITED
Patent: WO2004/13130 A1, 2004 ;
Location in patent: Page 181 ;
反应条件
1.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / 0 °C 1.2: pH 2.5 1.3: 12 h 2.1: potassium carbonate / ethanol / 80 °C View Scheme
参考文献
VERTEX PHARMACEUTICALS INCORPORATED; WANG, Tiansheng; HANZELKA, Brian; MUH, Ute; BEMIS, Guy; ZUCCOLA, Harmon, J.
Patent: WO2011/19405 A1, 2011 ;
WO 2011/019405 A1
