2-[乙酰氧基(苯基)甲基]丙烯酸甲酯合成路线 （共 24 条）
反应条件
1,4-diaza-bicyclo[2.2.2]octane in tetrahydrofuran
0.5 h; Heating; Yield given. Yields of byproduct given;
参考文献
ADOLOR CORPORATION; DOLLE, Roland, E.; LE BOURDONNEC, Bertrand; MARTIN, Pierre; MOESSNER, Christian Steffen; SPINDLER, Felix, Herbert; SPIELVOGEL, Dirk, Jost
Patent: WO2013/12871 A1, 2013 ;
Location in patent: Paragraph 0130 ;
反应条件
sodium hydride
T=20°C; 0.0833333 h;
参考文献
Nag, Somnath; Madapa, Sudharshan; Batra, Sanjay
Synthesis, 2008 , # 1 p. 101 - 109
反应条件
copper(l) iodide in tetrahydrofuran
5 h; Heating;
参考文献
Ranu, Brindaban C.; Chattopadhyay, Kalicharan; Jana, Ranjan
Tetrahedron Letters, 2007 , vol. 48, # 22 p. 3847 - 3850
反应条件
1: With bis(acetylacetonate)nickel(II); C28H21FeO2P in tetrahydrofuran
T=10°C; 72 h; Inert atmosphere;
2: With hydrogenchloride in tetrahydrofuran; water
Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Novak, Andrew; Calhorda, Maria Jose; Costa, Paulo Jorge; Woodward, Simon
European Journal of Organic Chemistry, 2009 , # 6 p. 898 - 903
