(4R-cis)-6-醛基-2,2-二甲基-1,3-二氧己环-4-乙酸叔丁酯合成路线 （共 25 条）
反应条件
1: in dimethyl sulfoxide T=35°C; Large scale; 2: With potassium carbonate in dimethyl sulfoxide T=70°C; 4 h; Large scale; SolventTimeTemperature;
参考文献
US2013/72688 A1, ;
Paragraph 0046-0050 ;
反应条件
caesium carbonate in dimethyl sulfoxide T=25 - 35°C; 3 h;
参考文献
WO2007/125547 A2, ;
Page/Page column 54; 71-72 ;
反应条件
potassium tert-butylate in tetrahydrofuran T=-30 - 20°C; Product distribution / selectivity;
参考文献
WO2010/77062 A2, ;
Page/Page column 13-14 ;
反应条件
2,2,6,6-tetramethylpiperidinyl-lithium in tetrahydrofuran 3 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 34, # 3 p. 513 - 516
反应条件
2,2,6,6-tetramethylpiperidinyl-lithium 1.) THF, RT, 30 min, 2.) THF, 3 h; Yield given. Multistep reaction;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 68, # 1 p. 364 - 372
