4-马来酰亚胺基丁酰肼三氟乙酸盐合成路线 （共 3 条）
反应条件
in dichloromethane 0.75 h;
参考文献
IMMUNOGEN, INC.; LI, Wei; FISHKIN, Nathan, Elliott; ZHAO, Robert, Yongxin; MILLER, Michael, Louis; CHARI, Ravi, V., J.
Patent: WO2010/91150 A1, 2010 ;
Location in patent: Page/Page column 168 ;
反应条件
1: GMBS With hydrazinecarboxylic acid tert-butyl ester 2: trifluoroacetic acid in dichloromethane
参考文献
WO2013/162757 A1, ;
Sheet 7 ;
反应条件
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol 2: hydrazinecarboxylic acid tert-butyl ester View Scheme
