(S)-3-(Boc-氨基)吡咯烷合成路线 （共 16 条）
反应条件
10 palladium on carbon; hydrogen in methanol T=20°C; 24 h;
参考文献
Tetrahedron Asymmetry, , vol. 21, # 11-12 p. 1511 - 1521
反应条件
hydrogen; palladium on activated charcoal in methanol T=21 - 25°C; P=1639.4 - 2616.8 Torr; 0.5 h;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 10 p. 1764 - 1773
反应条件
palladium in methanol
反应条件
acetic acid; palladium on activated charcoal in water 2 h; Heating;
参考文献
Heterocycles, , vol. 44, # 1 p. 213 - 225
反应条件
potassium hydrogensulfate; benzaldehyde in toluene
反应条件
potassium hydrogensulfate; benzaldehyde in toluene
反应条件
1: 10.3 g / Et3N / CH2Cl2 / 3 h / Ambient temperature 2: 5.51 g / NaBH4 / tetrahydrofuran; methanol / 45 - 55 °C 3: 5.30 g / Et3N / ethyl acetate / -20 - -5 °C 4: 94 percent / 2.5 h / 45 °C 5: 95 percent / AcOH / 10percent Pd/C / H2O / 2 h / Heating View Scheme
参考文献
Heterocycles, , vol. 44, # 1 p. 213 - 225
反应条件
ammonium hydroxide in acetonitrile 48 h; Ambient temperature; Yield given;
参考文献
Synthetic Communications, , vol. 28, # 21 p. 3919 - 3926
反应条件
1: NaBH4, CaCl2 / ethanol / 2 h / 0 °C 2: Et3N / CH2Cl2 / 1 h / -10 - 0 °C 3: aq. NH4OH / acetonitrile / 48 h / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 28, # 21 p. 3919 - 3926
反应条件
1: Et3N / CH2Cl2 / 1 h / -10 - 0 °C 2: aq. NH4OH / acetonitrile / 48 h / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 28, # 21 p. 3919 - 3926
