5-叠氮基-5-脱氧-2,3-O-异亚丙基-D-来苏糖酸-1,4-内酯合成路线 （共 5 条）
反应条件
1: With pyridine; trifluoromethylsulfonic anhydride in dichloromethane 2: With sodium azide in N,N-dimethyl-formamide
参考文献
Bleriot, Yves; Gretzke, Dirk; Kruelle, Thomas M.; Butters, Terry D.; Dwek, Raymond A.; Nash, Robert J.; Asano, Naoki; Fleet, George W.J.
Carbohydrate Research, 2005 , vol. 340, # 18 p. 2713 - 2718
反应条件
sodium azide in N,N-dimethyl-formamide T=0°C;
参考文献
Fleet, George W.J.; Petursson, Sigthor; Campbell, Arthur L.; Mueller, Richard A.; Behling, James R.; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 665 - 666
反应条件
1.1: 60 percent / CuSO4 / acetone 2.1: Tf2O; pyridine / CH2Cl2 2.2: 89 percent / NaN3 / dimethylformamide View Scheme
参考文献
Fleet, George W.J.; Petursson, Sigthor; Campbell, Arthur L.; Mueller, Richard A.; Behling, James R.; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 665 - 666
反应条件
1: 2.) hydrogen chloride / 1.) alkaline solution, Humphlett procedure for oxygenation , 2.) i-PrOH 2: 60 percent / anhyd. CuSO4 3: CH2Cl2 4: 89 percent / NaN3 / dimethylformamide / 0 °C View Scheme
参考文献
Fleet, George W.J.; Petursson, Sigthor; Campbell, Arthur L.; Mueller, Richard A.; Behling, James R.; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 665 - 666
反应条件
1: 97 percent / 4A MS / tetrahydrofuran / -78 °C 2: 91 percent / H2 / Pd / methanol View Scheme
参考文献
Fleet, George W.J.; Petursson, Sigthor; Campbell, Arthur L.; Mueller, Richard A.; Behling, James R.; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 665 - 666
