3,4-二甲氧基-beta-甲基-beta-硝基苯乙烯合成路线 （共 9 条）
反应条件
ammonium acetate T=90°C; 15 h;
参考文献
ASTRAZENECA AB
Patent: WO2005/61484 A1, 2005 ;
Location in patent: Page/Page column 41 ;
WO 2005/061484 A1
反应条件
pyridine; acetone Ueberschichten der Loesung mit Aether und Schuetteln mit Kalilauge;
参考文献
Schmidt,E. et al.
Chemische Berichte, 1922 , vol. 55, p. 1756
参考文献
Kauffmann
Chemische Berichte, 1917 , vol. 50, p. 635
Chemische Berichte, 1919 , vol. 52, p. 1431
反应条件
Schuetteln der mit Aether ueberschichteten Loesung mit Kalilauge;
参考文献
Schmidt,E. et al.
Chemische Berichte, 1922 , vol. 55, p. 1756
反应条件
aluminium trichloride; acetyl chloride in dichloromethane T=-30°C; 0.5 h;
参考文献
Kelkar, Shriniwas L.; Phadke, Chetan P.; Marina, Sister
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 5 p. 458 - 459
反应条件
L-Selectridereg; in tetrahydrofuran 0.5 h;
参考文献
Mourad, M. Soubei; Varma, Rajender S.; Kabalka, George W.
Synthesis, 1985 , # 6/7 p. 654 - 656
反应条件
indium; chloro-trimethyl-silane T=25°C; Reduction; Addition; 3.5 h;
参考文献
Yadav; Subba Reddy; Srinivas; Ramalingam
Synlett, 2000 , # 10 p. 1447 - 1449
反应条件
piperidine in methanol
1. 1 h/room temperature 2. 2 h/reflux;
参考文献
Niwas, Shri; Kumar, Shiv; Bhaduri, A. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 8 p. 725 - 726
反应条件
1: Fe, FeCl3, aq. HCl / 1 h / Heating
2: (i) NaOiPr, iPrOH, (ii) /BRN= 969135/
View Scheme
参考文献
Binovic,K.; Vrancea,S.
Chimica Therapeutica, 1968 , vol. 3, p. 313 - 320
