2-(4-氯苯基)-1H-吲哚-3-甲醛合成路线 （共 5 条）
反应条件
1: With trichlorophosphate T=0 - 35°C; 1 h; 2: With sodium hydroxide in water 0.5 h;
参考文献
Novo Nordisk A/S
Patent: US2007/10559 A1, 2007 ;
Location in patent: Page/Page column 13 ;
反应条件
1.1: acetic acid / ethanol / 40 °C / Heating 2.1: polyphosphoric acid / 0.25 h / 100 - 120 °C 3.1: trichlorophosphate / 0.5 h / 0 °C 3.2: 4.5 h / 0 - 40 °C View Scheme
参考文献
Kathrotiya, Harshad G.; Patel, Manish P.
Medicinal Chemistry Research, 2012 , vol. 21, # 11 p. 3406 - 3416
反应条件
1: N,N-dimethylaniline / 170 °C 2: POCl3 / 80 °C View Scheme
参考文献
Nyerges, Miklos; Pinter, Aron; Viranyi, Andrea; Bitter, Istvan; Toke, Laszlo
Tetrahedron Letters, 2005 , vol. 46, # 3 p. 377 - 380
反应条件
1: N,N-dimethylaniline / 170 °C 2: POCl3 / 80 °C View Scheme
参考文献
Nyerges, Miklos; Pinter, Aron; Viranyi, Andrea; Bitter, Istvan; Toke, Laszlo
Tetrahedron Letters, 2005 , vol. 46, # 3 p. 377 - 380
反应条件
1.1: polyphosphoric acid / 0.25 h / 100 - 120 °C 2.1: trichlorophosphate / 0.5 h / 0 °C 2.2: 4.5 h / 0 - 40 °C View Scheme
参考文献
Kathrotiya, Harshad G.; Patel, Manish P.
Medicinal Chemistry Research, 2012 , vol. 21, # 11 p. 3406 - 3416
