N-(2,3-二甲氧基苯基)乙酰胺合成路线 （共 7 条）
反应条件
1.1: thionyl chloride / benzene / 2 h / Heating 2.1: sodium azide / acetone; H2O / 1 h / 15 °C 3.1: benzene / 2 h / 60 °C 3.2: conc. HCl / 18 h / 80 °C 4.1: triethylamine / CH2Cl2 / 1 h View Scheme
参考文献
Whiteley, Chris G.
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 5 p. 1221 - 1227
反应条件
1.1: benzene / 2 h / 60 °C 1.2: conc. HCl / 18 h / 80 °C 2.1: triethylamine / CH2Cl2 / 1 h View Scheme
参考文献
Whiteley, Chris G.
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 5 p. 1221 - 1227
反应条件
1.1: sodium azide / acetone; H2O / 1 h / 15 °C 2.1: benzene / 2 h / 60 °C 2.2: conc. HCl / 18 h / 80 °C 3.1: triethylamine / CH2Cl2 / 1 h View Scheme
参考文献
Whiteley, Chris G.
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 5 p. 1221 - 1227
反应条件
triethylamine in dichloromethane 1 h;
参考文献
Whiteley, Chris G.
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 5 p. 1221 - 1227
反应条件
1: chloroform; bromine / 0 °C 2: hydrochloric acid 3: Diazotization View Scheme
参考文献
Simonsen; Rau
Journal of the Chemical Society, 1918 , vol. 113, p. 785
反应条件
1: chloroform; bromine / 0 °C
2: hydrochloric acid
3: Diazotization
4: glacial acetic acid; nitric acid
View Scheme
参考文献
Simonsen; Rau
Journal of the Chemical Society, 1918 , vol. 113, p. 785
反应条件
boron tribromide in dichloromethane
T=-78 - 20°C;
参考文献
Whiteley, Chris G.
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 5 p. 1221 - 1227
