5-亚苄基-2,2-二甲基-1,3-二恶烷-4,6-二酮合成路线 （共 31 条）
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; samarium(II) iodide tetrahydrofuran 1.) RT, 0.5 h, 2.) THF, 50 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Bao; Zhang
Synthetic Communications, 1995 , vol. 25, # 2 p. 143 - 148
反应条件
1: tetrahydrofuran; diethyl ether / 12 h / 0 - 20 °C / Inert atmosphere 2: potassium carbonate / N,N-dimethyl-formamide / 19 h / 0 - 20 °C 3: n-heptane; dichloromethane / 1 h / 20 °C View Scheme
参考文献
Mahoney, Stuart J.; Lou, Tiantong; Bondarenko, Ganna; Fillion, Eric
Organic Letters, 2012 , vol. 14, # 13 p. 3474 - 3477
反应条件
in ethanol 2 h; Heating;
参考文献
Strozhev, M. F.; Lielbriedis, I. E.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1990 , vol. 26, # 7 p. 790 - 792
Khimiya Geterotsiklicheskikh Soedinenii, 1990 , # 7 p. 947 - 949
反应条件
acetate buffer in water T=25°C; other buffers, various pH; Rate constant;
参考文献
Bernasconi, Claude F.; Leonarduzzi, Gianni D.
Journal of the American Chemical Society, 1980 , vol. 102, # 4 p. 1361 - 1366
反应条件
zinc(II) chloride
T=75°C; 0.5 h;
参考文献
Hu, Yi; Wei, Ping; Huang, He; Le, Zhang-Gao; Chen, Zhen-Chu
Synthetic Communications, 2005 , vol. 35, # 23 p. 2955 - 2960
反应条件
in ethanol
0.25 h; RefluxGreen chemistry;
参考文献
Kumar, Dhruva; Suresh; Sandhu, Jagir S.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 8 p. 1157 - 1160
反应条件
1: in tetrahydrofuran
T=0 - 20°C;
2: With hydrogenchloride
0.5 h;
参考文献
Fillion, Eric; Fishlock, Dan; Wilsily, Ashraf; Goll, Julie M.
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1316 - 1327
反应条件
toluene-4-sulfonic acid in dichloromethane
T=0°C; 0.166667 h;
参考文献
Chhabra, Baldev R.; Bolte, Matthew L.; Crow, Wilfrid D.
Australian Journal of Chemistry, 1984 , vol. 37, # 8 p. 1795 - 1797
反应条件
aluminum oxide; silica gel; periodic acid in dichloromethane
T=20°C; 0.5 h;
参考文献
Dakdouki, Saada C.; Villemin, Didier; Bar, Nathalie
European Journal of Organic Chemistry, 2012 , # 4 p. 780 - 784
反应条件
in acetic acid
Cyclization; 30 h; Heating;
参考文献
Suarez, Margarita; Ochoa, Estael; Verdecia, Yamila; Pita,Beatriz; Moran, Lourdes; et al.
Tetrahedron, 1999 , vol. 55, # 3 p. 875 - 884
