1: N-[5-(3,5-bis-trifluoromethyl-benzenesulfonyl methyl)-4-(4-fluoro-phenyl)-6-isopropyI-pyrimidin-2-yI]-N-methyl-methanesulfonamide With potassium carbonate in dimethyl sulfoxide T=35 - 40°C; 2: 1,1-Dimethylethyl 6-formyl-2,2-dimethyl-1,3-dioxane-4-acetate in dimethyl sulfoxide T=75 - 80°C; 12 h;