1: N-[4-(4-fIuoro-phenyl)-6-isopropyI-5-(pyridine-2-sulfonyImethyl)-pyrimidin-2-yl]-N-methyI-methanesuIfonamide With potassium carbonate in dimethyl sulfoxide T=35 - 40°C; 2: 1,1-Dimethylethyl 6-formyl-2,2-dimethyl-1,3-dioxane-4-acetate in dimethyl sulfoxide T=75 - 80°C; 12 h;