1,5-二甲氧基-2,4-二硝基苯合成路线 （共 48 条）
参考文献
Forrest,J.
Journal of the Chemical Society, 1960 , p. 574 - 580
反应条件
hydrogenchloride im geschlossenen Rohr;
参考文献
Blanksma; Meerum; Terwogt
Recueil des Travaux Chimiques des Pays-Bas, 1902 , vol. 21, p. 289
参考文献
Blanksma; Meerum Terwogt
Recueil des Travaux Chimiques des Pays-Bas, 1902 , vol. 21, p. 288
反应条件
1: 63 percent / sodium polysulfide / H2O / 3 h / Heating 2: 99 percent / Cu(OAc)2 / dimethylformamide / 7 h / Heating 3: 1.) CDI / 1.) DMF, 40 deg C, 10 min, 2.) DMF, 20 deg C, 17 h 4: 49 percent / PPE / 2 h / 100 °C View Scheme
参考文献
Lee; Wilson; Ferry; Van Zijl; Pullen; Denny
Journal of Medicinal Chemistry, 1996 , vol. 39, # 13 p. 2508 - 2517
反应条件
1: methanol With sodium
2: DFDNB 18 h;
参考文献
Piotrowski, David W.; Rogers, Bruce N.; McWhorter JR., William W.; Walker, Daniel Patrick; Corbett, Jeffrey W.; Groppi JR., Vincent E.; Rudmann, Daniel G.
Patent: US2003/236287 A1, 2003 ;
Location in patent: Page 32, 33 ;
US 20030236287 A1
反应条件
hydrogenchloride in methanol; water
参考文献
The Dow Chemical Company
Patent: US5414130 A1, 1995 ;
反应条件
oxygen; nitrogen(IV) oxide; iron (III) acetylacetonate in 1,2-dichloro-ethane
T=0°C; 24 h;
参考文献
Suzuki, Hitomi; Yonezawa, Shuji; Nonoyama, Nobuaki; Mori, Tadashi
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 19 p. 2385 - 2389
反应条件
sodium methylate in methanol; toluene
参考文献
Clairol Incorporated
Patent: US4566876 A1, 1986 ;
反应条件
nitric acid in acetic acid
T=-5°C; 1 h; Further byproducts given;
参考文献
Natoli, Maria C.; Ceraulo, Leopoldo; Lamartina, Liliana
Gazzetta Chimica Italiana, 1989 , vol. 119, # 3 p. 145 - 152
反应条件
methanesulfonic acid; nitrogen(IV) oxide; ozone in acetonitrile
T=-10°C; Nitration; 1.5 h; Title compound not separated from byproducts;
参考文献
Nose; Suzuki
Synthesis, 2000 , # 11 p. 1539 - 1542
