S-3-氨基奎宁环二盐酸盐合成路线 （共 6 条）
反应条件
methanol; sodium hydroxide T=50°C; 1 h;
参考文献
US2008/200681 A1, ;
Page/Page column 10 ;
反应条件
in thionyl chloride; dichloromethane
参考文献
Odzak, Renata; Tomic, Srdanka
Bioorganic Chemistry, 2006 , vol. 34, # 2 p. 90 - 98
反应条件
in toluene T=40 - 65°C; Inert atmosphere;
参考文献
DR. REDDY'S LABORATORIES LTD.; DR. REDDY'S LABORATORIES, INC.; KATKAM, Srinivas; SAGYAM, Rajeshwar Reddy; SUNKARA, Vishnuvardhan; MUNAGALA, Sridhar; MUTTAVARAPU, Murali Mohan
Patent: WO2010/56656 A2, 2010 ;
Location in patent: Page/Page column 22 ;
反应条件
in N-methyl-acetamide; dichloromethane; water
参考文献
Syntex (U.S.A.) Inc.
Patent: US5202333 A1, 1993 ;
反应条件
T=110 - 115°C; Condensation; 45 h;
参考文献
Kowalczyk, Bruce A.
Synthesis, 2000 , # 8 p. 1113 - 1116
