2-苯基-1,3-恶唑-4-甲酰氯合成路线 (共 8 条)
反应条件
oxalyl dichloride in dichloromethane; N,N-dimethyl-formamide 3 h; Inert atmosphere;
参考文献
Stefely, Jonathan A.; Palchaudhuri, Rahul; Miller, Patricia A.; Peterson, Rebecca J.; Moraski, Garrett C.; Hergenrother, Paul J.; Miller, Marvin J.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 8 p. 3389 - 3395
参考文献
Cornforth et al.
Journal of the Chemical Society, 1949 , p. 1549,1551
反应条件
Destillation unter vermindertem Druck;
参考文献
Cornforth
Chem. Penicillin, <Princeton 1949>, S. 688, 699, 723
反应条件
1: NaBH4 / dioxane 2: SOCl2 View Scheme
参考文献
Jansen,A.B.A.; Szelke,M.
Journal of the Chemical Society, 1961 , p. 405 - 411
反应条件
1: NaBH4 / dioxane 2: PBr5 / benzene 3: methanol / Heating View Scheme
参考文献
Jansen,A.B.A.; Szelke,M.
Journal of the Chemical Society, 1961 , p. 405 - 411
反应条件
Pd-BaSO4; thiourea; xylene
Hydrogenation;
参考文献
Cornforth et al.
Journal of the Chemical Society, 1949 , p. 1549,1551
反应条件
1: NaBH4 / dioxane
2: PBr5 / benzene
View Scheme
参考文献
Jansen,A.B.A.; Szelke,M.
Journal of the Chemical Society, 1961 , p. 405 - 411
反应条件
sodium tetrahydroborate in 1,4-dioxane
参考文献
Jansen,A.B.A.; Szelke,M.
Journal of the Chemical Society, 1961 , p. 405 - 411