反应条件
1: 80 percent / KF.2H2O / dimethylformamide 2: 96 percent / imidazole / dimethylformamide 3: 93 percent / Et2NH, Pd(PPh3)4, CuI / 15 h / Ambient temperature 4: 92 percent / PPh3, CBr4 / CH2Cl2 / -40 - 0 °C 5: 90 percent / 100 °C 6: LDA / tetrahydrofuran / -78 deg C, 8 h; -20 deg C, 1 h; room temp., 1 h 7: 60 percent / H2 / Lindlar catalyst / CH2Cl2 / 22 h / Ambient temperature 8: 73 percent / n-Bu4NF / tetrahydrofuran / 5 h / Ambient temperature View Scheme
参考文献
Nicolaou, K. C.; Zipkin, R. E.; Dolle, R. E.; Harris, B. D.
Journal of the American Chemical Society, 1984 , vol. 106, # 12 p. 3548 - 3551
