反应条件
1: 98 percent / Ti(O-i-Pr)4, (R,R)-1,2-diaminocyclohexane ditrifluoromethanesulfonamide / toluene; various solvent(s) / 3 h / 0 °C 2: diphenylphosphoryl azide, DBU / toluene / 0-5 deg C -> room temperature 2-3 h, 16 h 3: LiAlH4 / tetrahydrofuran; toluene / 8 h / 23 °C 4: 98 percent / HCl / toluene / 1.33 h / 100 °C 5: 80 percent / DBU / acetonitrile / 1 h View Scheme
参考文献
Storace, Louis; Anzalone, Luigi; Confalone, Pat N.; Davis, Wayne P.; Fortunak, Joseph M.; Giangiordano, Mark; Haley Jr., James J.; Kamholz, Kenneth; Li, Hui-Yin; Ma, Philip; Nugent, William A.; Parsons Jr., Rodney L.; Sheeran, Patrick J.; Silverman, Charlotte E.; Waltermire, Robert E.; Wood, Christopher C.
Organic Process Research and Development, 2002 , vol. 6, # 1 p. 54 - 63
