反应条件
1: acetic acid; ammonium acetate / 100 °C 2: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / |Reflux 3: ethanol / 14 h / |Reflux 4: pyridine / dichloromethane / 1.5 h / 0 - 20 °C 5: trichlorophosphate / acetonitrile / 1 h / |Reflux; |Inert atmosphere 6: [[(η6-p-cymene)((1S,2S)-N-p-toluenesulfonyl-1,2-diphenylethylenediamine)]Ru]; formic acid; triethylamine / N,N-dimethyl-formamide / 20 °C 7: water; sodium hydroxide / ethanol / 3 h / 20 °C 8: thionyl chloride / dichloromethane / 1.5 h / 0 - 20 °C 9: sodium hydrogencarbonate / dichloromethane / 1.5 h / 20 °C View Scheme
参考文献
Sun, Haifeng; Zhu, Liyuan; Yang, Huicui; Qian, Wangke; Guo, Lin; Zhou, Shengbin; Gao, Bo; Li, Zeng; Zhou, Yu; Jiang, Hualiang; Chen, Kaixian; Zhen, Xuechu; Liu, Hong
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 4 p. 856 - 868
