4-乙氧基-3-甲氧基苯甲醛合成路线 （共 41 条）
反应条件
1: vanillin With sodium hydroxide; 18-crown-6 ether in water; isopropyl alcohol 0.5 h; 2: ethyl bromide in water; isopropyl alcohol T=60°C;
参考文献
EP2351730 A1, ;
Page/Page column 9 ;
反应条件
potassium carbonate in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; water; acetonitrile
反应条件
tert.-butylhydroperoxide; air; meso-tetra(2,6-dichloro-3-sulphonatophenyl)porphyrin iron chloride in acetonitrile 2 h; Ambient temperaturepH=3;
参考文献
Canadian Journal of Chemistry, , vol. 73, # 12 p. 2153 - 2157
反应条件
1: 1-(4-ethoxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)-propane-1,3-diol With water; oxygen; α,α'-azodiizobutyramidine-dihydrochloride in acetone T=60°C; pH=5; 3 h; Sodium acetate buffer; 2: N,O-bis(trimethylsilyl) trifluoroacetamide With pyridine T=60°C; 1 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 7 p. 2481 - 2491
反应条件
1: 1-(4-ethoxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)-propane-1,3-diol With water; oxygen; α,α'-azodiizobutyramidine-dihydrochloride in acetone T=60°C; pH=5; 3 h; Sodium acetate buffer; 2: acetic anhydride With pyridine T=20°C; 12 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 7 p. 2481 - 2491
反应条件
1: 1-(4-ethoxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)-propane-1,3-diol With water; α,α'-azodiizobutyramidine-dihydrochloride in acetone T=60°C; pH=5; 3 h; Inert atmosphereSodium acetate buffer; 2: N,O-bis(trimethylsilyl) trifluoroacetamide With pyridine T=60°C; 1 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 7 p. 2481 - 2491
反应条件
1: 1-(4-ethoxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)-propane-1,3-diol With water; α,α'-azodiizobutyramidine-dihydrochloride in acetone T=60°C; pH=5; 3 h; Inert atmosphereSodium acetate buffer; 2: acetic anhydride With pyridine T=20°C; 12 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 7 p. 2481 - 2491
反应条件
chromium(VI) oxide; perchloric acid; acetonitrile T=0 - 5°C; 3 h; Further byproducts given;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 41, # 9 p. 1507 - 1512
反应条件
1: 1-(4-ethoxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)-propane-1,3-diol With tert.-butylhydroperoxide; titanium(III) chloride; water in acetone T=20°C; 2: acetic anhydride With pyridine T=20°C; 12 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 7 p. 2481 - 2491
反应条件
1: K2CO3 / diethyl ether 2: K2CO3 / diethyl ether View Scheme
参考文献
Phytochemistry (Elsevier), , vol. 13, p. 2845 - 2847
