N,N-二乙基-4-氨基苯甲醛合成路线 （共 64 条）
反应条件
1: benzene / 4 h / Heating
2: NaBH4 / methanol / 3 h
3: KOH
4: 56.7 percent / ethanol / 3 h / Heating
5: 1.) 50percent NaH
View Scheme
参考文献
Hori; Yoshida; Murakami; Takeno; Nakano; Nitta; Tsuda; Kishimoto; Saikawa
Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 3 p. 684 - 698
反应条件
1: benzene / 4 h / Heating
2: NaBH4 / methanol / 3 h
3: KOH
4: 56.7 percent / ethanol / 3 h / Heating
5: 1.) 50percent NaH
View Scheme
参考文献
Hori; Yoshida; Murakami; Takeno; Nakano; Nitta; Tsuda; Kishimoto; Saikawa
Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 3 p. 684 - 698
反应条件
1: benzene / 4 h / Heating
2: NaBH4 / methanol / 3 h
3: KOH
4: 56.7 percent / ethanol / 3 h / Heating
5: 1.) 50percent NaH
View Scheme
参考文献
Hori; Yoshida; Murakami; Takeno; Nakano; Nitta; Tsuda; Kishimoto; Saikawa
Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 3 p. 684 - 698
反应条件
water; potassium hydroxide
T=20°C; 0.2 h;
参考文献
Kamakshi; Latha, S. Swarna; Reddy
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2010 , vol. 49, # 7 p. 944 - 947
反应条件
sodium hydroxide in ethanol
4 h; Reflux;
参考文献
Zou, Qianli; Zhao, Yuxia; Makarov, Nikolay S.; Campo, Jochen; Yuan, Hao; Fang, De-Cai; Perry, Joseph W.; Wu, Feipeng
Physical Chemistry Chemical Physics, 2012 , vol. 14, # 33 p. 11743 - 11752
反应条件
in benzene
20 h; Heating;
参考文献
Robbe; Fernandez; Dubief; et al.
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 3 p. 235 - 243
反应条件
diethyl ether
beim Erhitzen des Reaktionsproduktes auf 120grad;
参考文献
Sachs,F.; Michaelis
Chemische Berichte, 1906 , vol. 39, p. 2166
反应条件
1: ethanol
2: NaBH4 / methanol; H2O
View Scheme
参考文献
Gardner,T.S. et al.
Journal of Medicinal and Pharmaceutical Chemistry, 1961 , vol. 3, p. 241 - 252
参考文献
Hoffmann-La Roche
Patent: US2686784 , 1950 ;
Full Text Show Details
Doja; Prasad
Journal of the Indian Chemical Society, 1942 , vol. 19, p. 377,378
24 <1947> 301, 302
参考文献
Mazza; Montanari; Pavanetto
Farmaco, Edizione Scientifica, 1976 , vol. 31, # 5 p. 334 - 344
