3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
Multi-step reaction with 3 steps 1: 0.5 g / potassium hydroxide / ethanol; H2O / 48 h / Ambient temperature2: 0.3 g / selenium dioxide / 3-methyl-butan-1-ol / 72 h / Heating3: 0.15 g / H2 / Pd/C (10percent) / acetic acid
参考文献
Bhardwaj, D. K.; Gupta, A. K.; Jain, A.; Shrawat; V. K. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 261 - 263
反应条件
Multi-step reaction with 3 steps 1: 80 percent / piperidine2: CuCl / diethyl ether / 3 h / ice-bath3: aq.KOH / 3 h / Heating
参考文献
Selvaraj, S.; Rajendran, A. S.; Arumugam, N. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 1047 - 1049
反应条件
Multi-step reaction with 4 steps 1: 80 percent / piperidine2: CuCl / diethyl ether / 3 h / ice-bath3: aq.KOH / 3 h / Heating4: 71 percent / aq.H2SO4 / 8 h / Heating
参考文献
Selvaraj, S.; Rajendran, A. S.; Arumugam, N. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 1047 - 1049
反应条件
Multi-step reaction with 3 steps 1: 69 percent / HCl gas / CHCl3 / 1 h / 0 °C2: 1.) BuLi / 1.) THF, - 78 deg C, 30 min; 2.) THF, -78 deg C, 90 min; 3.) THF, -78 deg C, 2 h3: 30 percent / mercury(II) trifluoroacetate / tetrahydrofuran / 48 h / Ambient temperature
参考文献
Pelter, Andrew; Ward, Robert S.; Pritchard, Martyn C.; Kay, I. Trevor Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 1603 - 1614
反应条件
Multi-step reaction with 6 steps 1: p-TsOH / benzene / Heating2: NaBH4 / methanol / 2 h / Ambient temperature3: CH2Cl2 / 2 h / 0 °C4: m-chloroperbenzoic acid (m-CPBA), NaHCO3 / CH2Cl2 / 2.5 h / -30 °C5: trifluoroacetic anhydride (TFAA) / toluene / 0.01 h / Heating6: Raney Ni / ethanol / 3 h / Heating
参考文献
Takano, Seiichi; Iida, Hirokazu; Inomata, Kohei; Ogasawara, Kunio Heterocycles, 1993 , vol. 35, # 1 p. 47 - 52
反应条件
Multi-step reaction with 4 steps 2: LAH3: benzene / 0.75 h / Ambient temperature4: 55.6 percent / FeSO4*7H2O, NH4OH / H2O / 3 h / Heating
参考文献
Joshi; Chaudhari; Mogera Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 5 p. 431 - 434
